research Clinical Use of 5α-Reductase Inhibitors
Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.
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540-570 / 1000+ results research Phytochemicals With Anti 5-Alpha-Reductase Activity: A Prospective For Prostate Cancer Treatment
Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.
research Camellia Seed Cake Extract Supports Hair Growth by Abrogating the Effect of Dihydrotestosterone in Cultured Human Dermal Papilla Cells
Camellia seed cake extract may help hair growth by blocking the hair loss effects of a hormone called DHT.
research Effects of the 5α-Reductase Inhibitor Finasteride on Serum Levels of Gonadal, Adrenal, and Hypophyseal Hormones and Its Clinical Significance: A Prospective Clinical Study
Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.
research Inhibition of Rat 5α-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of Quercus Acutissima Cortex
An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.
research Inhibitory Activities of Puerariae Flos Against Testosterone 5α-Reductase and Its Hair Growth Promotion Activities
Puerariae Flos extract may help treat hair loss by blocking a hair loss-related enzyme and promoting hair growth.
research Androgenic Alopecia: A Counterproductive Outcome of the Anabolic Effect of Androgens
Male pattern baldness is an unintended side effect of the body's use of androgens for muscle growth, especially in those genetically prone to it.
research Steroid 5α-Reductase 2 Deficiency Leads to Reduced Dominance-Related and Impulse-Control Behaviors
Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.
research Androgenic Alopecia: Pathogenetic Mechanisms and Therapeutic Approaches
The document concludes that current treatments for androgenic alopecia are not fully effective, but new therapies like botulinum toxin and PRP show promise, and future gene therapy could be beneficial.
research Effects of Parthenolide on Androgenetic Alopecia in Mice and Human Follicle Dermal Papilla Cells
Parthenolide promotes hair growth in mice and may influence pathways related to male pattern baldness.
research Saccharomyces Cerevisiae BLYAS, A New Bioluminescent Bioreporter For Detection Of Androgenic Compounds
The engineered yeast strain BLYAS can quickly and sensitively detect androgenic chemicals.
research 5α-Reductase Activity in the Prostate
Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.
research The Role of Androgens in Hormone Replacement Therapy
Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.
research Dihydrotestosterone and 5α-Reductase: Role in Hair Loss and Prostate Health
Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.
research Pharmacophore and Atom-Based 3D QSAR Studies on the Novel 5-Alpha-Reductase Inhibitors
The developed model can predict effective 5-alpha-reductase enzyme inhibitors.
research The Dihydrotestosterone Hypothesis of Prostate Cancer and Its Therapeutic Implications
The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
research Nonsteroidal Inhibitors of Human Type I Steroid 5α-Reductase
New compounds called benzoquinolinones may treat conditions linked to excess DHT.
research Selective Non-Steroidal Inhibitors of 5α-Reductase Type 1
Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.
research Clinical Patterns of Hair Loss in Men
The document concludes that more research is needed to understand hair loss in men and to find new treatments.
research Endocrine Profile of the VCD-Induced Perimenopausal Model Rat
The rat model showed early perimenopause with regular cycles and low hormones, and late perimenopause with irregular cycles and higher hormone levels.
research Adrenal and Gonadal Activity, Androgen Concentrations, and Adult Height Outcomes in Boys With Silver-Russell Syndrome
Higher androgen levels during puberty are linked to shorter adult height in boys with Silver-Russell syndrome.
research Androgenic Alopecia: Recent Understanding Of The Androgenetic Receptor-Mediated Molecular Mechanisms And Current Pharmacotherapy
Androgenic alopecia is mainly caused by DHT, and new treatments focus on hair regeneration and aging factors.
research Progress on Mitochondria and Hair Follicle Development in Androgenetic Alopecia: Relationships and Therapeutic Perspectives
Maintaining healthy mitochondria may help treat hair loss.
research The Potential of Androgenic Alopecia Management from Plant Derivatives
Plant extracts like Avicennia marina, Boehmeria nipononivea, and Camellia sinensis could potentially treat hair loss with fewer side effects than synthetic drugs.
research 5α-Reductase Inhibitors and Prostatic Disease
5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.
research Synergistic Therapeutic Effect of Ginsenoside Rg3 Modified Minoxidil Transfersomes on Androgenic Alopecia in C57BL/6 Mice
Ginsenoside Rg3 combined with minoxidil was more effective in treating hair loss in mice.
research Development and Evaluation of Finasteride Niosomes Targeting Hair Follicles for Androgenic Alopecia Management
Finasteride niosomes were developed and found to be effective in treating hair loss, with better results than commercial minoxidil, and could be a promising topical treatment for hair loss.
research Specific Morphogenetic Events in Mouse External Genitalia Sex Differentiation Are Dependent Upon Androgens and Estrogens
Mouse genital development depends on male or female hormones for specific features.
research Androgenetic Alopecia: Drug Safety and Therapeutic Strategies
Personalized treatment with inhibitors, minoxidil, and laser therapy helps hair loss.
research Cosmetic Concerns Among Men
More men are getting cosmetic procedures, mainly for aging, hair loss, and to keep masculine features, with growing interest in both surgical and noninvasive treatments.