research Abstracts
Finasteride significantly increases scalp hair and prevents hair loss in young and middle-aged men.
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research Analysis of Gene Expression in Isolated Single Hair Follicles Using Semiquantitative Reverse-Transcriptase Polymerase Chain Reaction
Researchers developed a new way to measure gene activity in single hair follicles and found that a specific gene's activity changes with different amounts and times of treatment.
research Diseases of the Hair and Scalp
The book is a valuable resource for understanding hair and scalp problems but could be updated with more information on certain conditions.
research Expert Medical Testimony on Penicillamine Side Effects
Penicillamine can cause taste problems due to copper loss, which can be fixed with copper or zinc supplements.
research Finasteride
research Design, Synthesis, and Biological Activity of TLR7-Based Compounds for Chemotherapy-Induced Alopecia
TLR7-based compounds may help manage chemotherapy-induced hair loss.
research Ornithine Decarboxylase as a Target for Chemoprevention of Basal and Squamous Cell Carcinomas in Ptch1+/– Mice
Inhibiting ornithine decarboxylase may help prevent certain skin cancers.
research Trichilemmal Carcinoma Metastatic to Parotid Gland: First Report of Fine Needle Aspiration Cytology Features
Trichilemmal carcinoma can spread to the parotid gland and be diagnosed using fine-needle aspiration cytology.
research Trichothiodystrophy Hair Shafts Display Distinct Ultrastructural Features
Trichothiodystrophy hair is structurally abnormal with protein and organization issues.
research The JAK/STAT Signaling Pathway: From Bench to Clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
research The Selective Androgen Receptor Modulator GTx-024 (Enobosarm) Improves Lean Body Mass and Physical Function in Healthy Elderly Men and Postmenopausal Women: Results of a Double-Blind, Placebo-Controlled Phase II Trial
Enobosarm significantly increased muscle mass and improved physical function in elderly men and postmenopausal women without serious side effects.
research A Slow-Cycling LGR5 Tumor Population Mediates Basal Cell Carcinoma Relapse After Therapy
A small group of slow-growing cells causes basal cell carcinoma to return after treatment.
research Scientific Opinion on the Tolerable Upper Intake Level for Selenium
Adults should not consume more than 255 micrograms of selenium per day to avoid risk of hair loss and other side effects.
research Principles of Chemotherapy
Chemotherapy is crucial for treating gynecological cancers but requires careful management due to severe side effects.
research Climate Change, Human Migration, and Skin Disease: Is There a Link?
Climate change can cause migration, spreading and increasing skin diseases.
research Finasteride Enhances the Generation of Human Myeloid-Derived Suppressor Cells by Up-Regulating the COX2/PGE2 Pathway
research Hair Follicle Dystrophy in a Litter of Domestic Cats Resembling Lanceolate Hair Mutant Mice
A litter of cats had a hair condition similar to a mouse mutation, leading to hair loss and abnormal hair and skin.
research Tinea Corporis and Tinea Capitis
Ringworm of the body and scalp is treated with antifungal creams and oral medication, and children with scalp ringworm don't need to miss school.
research Complete Pseudo-Anodontia in an Adult Woman with Pseudo-Hypoparathyroidism Type 1a: A New Additional Nonclassical Feature?
A woman with a rare hormone resistance condition also had missing teeth and hair loss, which might be new symptoms of her genetic disorder.
research Effects of Acute UVB on Retinoid Metabolism
UVB exposure increases skin proteins for retinoic acid synthesis and shifts their location, possibly affecting skin repair.
research Persistent Gynecomastia Due to Short-Term Low-Dose Finasteride for Androgenetic Alopecia
A man's breast enlargement from low-dose finasteride for hair loss didn't go away, even with treatment, and might be more common than reported.
research Case 1: Intractable Rash in a 7-Month-Old Boy
The 7-month-old boy has a persistent rash that doesn't improve with typical skin treatments.
research Structural and Molecular Hair Abnormalities in Trichothiodystrophy
TTD hair brittleness is caused by multiple structural abnormalities.
research Long-Term Differential Changes in Mouse Intestinal Metabolomics After Gamma and Heavy Ion Radiation Exposure
Heavy ion radiation has a more severe and long-lasting effect on mouse intestinal metabolites than gamma radiation.
research Tyrosinase Depletion Prevents the Maturation of Melanosomes in the Mouse Hair Follicle
Reducing Tyrosinase prevents mature color pigment cells from forming in mouse hair.
research Tissue-Selective Regulation of Androgen-Responsive Genes
The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.
research Patient-Level Adverse Event Patterns in a Single-Institution Study of the Multi-Kinase Inhibitor Sorafenib
Sorafenib often causes mucositis, hand-foot syndrome, rash, alopecia, diarrhea, and fatigue.
research Culture of Amelanotic Melanocytes Derived from Human Fetal Hair Follicles
Melanocytes from human fetal hair follicles were successfully cultured, showing potential for hair disease research and clinical use.
research Logic-Based Modeling and Drug Repurposing for the Prediction of Novel Therapeutic Targets and Combination Regimens Against E2F1-Driven Melanoma Progression
Tadalafil and Finasteride may help treat aggressive melanoma.
research Challenges Associated With the Identification of Germline Variants on Myeloid Malignancy Genomic Profiling—A Singaporean Experience
Genomic profiling for myeloid cancers can find important inherited mutations, but it's challenging when these mutations aren't related to the patient's symptoms.