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This review synthesizes recent research on how Wnt signaling regulates skin, hair follicle, and nail regeneration, highlighting its compartment-specific roles and discussing targeted strategies for treating conditions like alopecia, chronic wounds, and skin cancer.

This review highlights significant advancements over the past 20 years in understanding the unique dermatological characteristics and needs of skin of color populations, though continued efforts are needed to address remaining disparities.

In this study, a 90-day course of a plant-based supplement significantly improved hair density, skin hydration, and nail growth among participants with dermatological concerns, while also reducing hair fall and pigmentation, without adverse effects.

This article describes a case of selenium poisoning in a 36-year-old man who experienced hair loss, nail changes, and paresthesias after taking selenium-containing vitamin tablets.

This case report documents the first confirmed mutation-proved instance of Clouston syndrome in a large Chinese-Malaysian family, linked to the c.263C>T (A88V) mutation in the GJB6 gene, with no available treatment but highlighting the importance of genetic counseling.

This case report describes a novel NECTIN4 gene mutation linked to ED-syndactyly syndrome 1 in a young girl, contributing to the understanding of this rare ectodermal dysplasia.

This review explores the biomechanical factors and signaling systems, like Wnt, involved in the pathophysiology of psoriatic nail lesions and reports no new results.

This study suggests that onychopapilloma may originate from the nail bed rather than the nail matrix, with nail bed-related keratins and HK31 potentially serving as diagnostic markers.

This case report describes a 60-year-old male with vitamin A toxicity leading to severe liver disease and symptoms that resolved following liver transplantation, suggesting transplantation as a treatment option for noncirrhotic portal hypertension when symptoms do not improve after stopping vitamin A.

This case report describes erosive pustular dermatosis of the scalp in a patient undergoing gefitinib treatment for lung cancer, and reviews literature on drug-induced cases of this rare condition.

This study found that patients on maintenance hemodialysis commonly experience cutaneous symptoms, with pigmentation and nail disorders being the most prevalent.

This review discusses biotin supplementation for dermatological conditions and highlights the lack of strong evidence supporting its efficacy, as well as the potential for laboratory testing interference.

In this study, three patients with alopecia areata exhibited spotty absence of the whiteness of their nail lunulae, potentially due to defects in the matrical epithelium.

This retrospective study found a variety of dermatological adverse events associated with antineoplastic treatments, often leading to changes or suspension of cancer therapies in affected patients.

In this descriptive study, researchers assessed the most common short-term side effects of anthracycline and taxane-based chemotherapy in 122 Moroccan women with localized breast cancer, documenting frequent systemic, gastrointestinal, dermatological, neurological, musculoskeletal, and ocular toxicities.

This case report details a rare instance of eruptive vellus hair cysts in a 12-year-old male, highlighting its atypical morphology and axillary distribution, which has not been previously documented.

This case report describes an 8-year-old boy in Saudi Arabia diagnosed with IFAP syndrome, highlighting its distinct characteristics and distinguishing features from similar conditions, and notes successful genetic confirmation of the disorder.

This case report describes a patient with Clouston syndrome who developed squamous cell carcinoma, highlighting the need for regular follow-up in patients with chronic paronychia that do not respond to conventional treatments.

This case report describes two instances of habit tic nail deformities associated with alopecia areata.

This study identifies various nail changes in alopecia areata, which can affect quality of life, and suggests that while spontaneous improvement is possible, further research is needed to refine treatment strategies.

In this case report, a 17-year-old male on sodium valproate therapy developed rare longitudinal melanonychia, suggesting sodium valproate can induce nail pigmentation as a side effect.

This discussion covers various nail disorders, including tumors and non-neoplastic issues, emphasizing that not all nail abnormalities are due to fungal infections, but it reports no new clinical findings.

More research is needed to understand how hair keratins work and their role in hair disorders.

This review explores the efficacy and outcomes of using JAK inhibitors for treating alopecia areata, noting advancements in understanding the disease's pathomechanisms and suggesting that JAK inhibitors may offer targeted therapeutic benefits by blocking specific inflammatory pathways involved in this chronic condition.

The skin is essential for protection, temperature control, and immune defense.

Stem cells in mouse nails are found in the nail matrix and may control nail growth.

This study suggests that female patients with alopecia areata, especially those with nail abnormalities and atopic diseases, may have higher rates of coexisting autoimmune diseases.

This study identified dose levels of selenium that can produce toxicity, noting that doses as low as 2-3 µg Se/kg bw/day can lead to adverse effects, and a human mortality study linked 300 µg/day consumption to increased death risk.

This review discusses the enigmatic nature of frontal fibrosing alopecia and reports no clinical results; the authors stress the need for further research.