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The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.

Low Vitamin D receptor levels in breast cancer are linked to worse outcomes and more bone metastases, and could be a marker for prognosis.

The document concludes that more research is needed to reduce frequent hospital visits, addiction medicine education improves with specific training, early breast cancer surgery findings are emerging, nipple smears are not very accurate, surgery for older melanoma patients doesn't extend life, a genetic condition in infants can often be treated with one drug, doctors are inconsistent with blood clot medication, a certain gene may protect against cell damage, muscle gene overexpression affects many other genes, and some mitochondrial genes are less active in mice with tumors.

Antiviral drugs, especially daclatasvir, may be a new treatment for a rare skin disease, improving survival and reducing symptoms in mice.

Accurate diagnosis of APL is crucial to avoid unnecessary treatments.

A second domain of high sulfur KAP genes on chromosome 21q23 is crucial for hair structure.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.

A new gene mutation may allow some piebaldism patients to regain skin color in white patches.

Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.

A new mutation in the XEDAR gene might cause a rare skin condition called hypohidrotic ectodermal dysplasia.

The research suggests that p63 and TGF-β1 may help determine tumor type and malignancy in hair follicle and sebaceous tumors.

The conclusion is that analyzing RNA from skin oils is a promising way to understand skin diseases.

Scientists successfully created mouse hair proteins in the lab, which are stable and similar to natural hair.

Four-amino acid part makes enzyme sensitive to finasteride.

A genetic mutation caused severe rickets and alopecia in an Indian patient, but high-dose calcium and phosphate treatment improved their condition.

The R343H mutation in the VDR gene causes vitamin D-resistant rickets with alopecia by impairing specific gene activity.

Clim proteins are essential for maintaining healthy corneas and hair follicles.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

S100A3 protein is crucial for hair shaft formation in mice.

Accurate clinical, histological, and genetic methods are key for understanding and treating hair disorders.

Flightless I protein affects hair growth, with low levels delaying it and high levels increasing hair length in rodents.

People with X-linked hypohidrotic ectodermal dysplasia have no sweat ducts and less, thinner hair.

The S250C variant in a gene may cause autoimmunity and immunodeficiency by impairing protein function.

The home-use IPL device effectively reduced hair and delayed its regrowth after six months of use, with users happy and no negative side effects.

Impaired autophagy may cause hair loss by triggering early catagen.

AP-2α and AP-2β proteins are essential for healthy adult skin and hair.