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The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.

Fish oil increased cell growth and macrophages in the skin but didn't affect COX-2 expression.

Skin, hair, and nail changes can help detect eating disorders early.

Men and women respond differently to drugs for COVID-19, high cholesterol, and diabetes, which suggests a need for personalized treatments.

Sdr16c5 and Sdr16c6 genes regulate a key point in lipid production that affects eye and skin gland function.

Nitroxide drugs can safely and effectively treat age-related diseases like macular degeneration and cardiovascular issues.

The Polish medical societies have redefined metabolic syndrome and recommend lifestyle changes, certain medications, and possibly bariatric surgery for treatment. They also discuss managing related health conditions.

Vertical sleeve gastrectomy improved metabolism, behavior, and reproduction in obese rats with PCOS.

Microemulsions could improve skin drug delivery but face challenges like complex creation and potential toxicity.

Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

The fish oil-based gel with imiquimod improves skin cancer treatment and reduces inflammation.

Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.

Lung and liver macrophages protect our tissues and their dysfunction can cause various diseases.

Insulin might be involved in causing hair loss and acne.

Menopause can cause hair thinning and texture changes due to hormonal and metabolic shifts.

Early diagnosis and personalized treatment are crucial for managing PCOS and preventing complications.

Different treatments help heal leg ulcers depending on their type, with new therapies showing promise for chronic wounds.

Probiotics show promise for health benefits but need more research to understand how they work.

Linoleic acid is essential for healthy skin, and while deficiency is rare in Western societies, it can cause dry, scaly skin and hair loss.

Pigs can make some essential fats and don't need them all in their diet to grow and stay healthy.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Saw palmetto supplements may reduce prostate cancer cell growth without being toxic.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

The extract reduced sebum production and promoted hair growth.

English springer spaniels are more prone to severe sebaceous adenitis than standard poodles.

sPLA2-IIE is crucial for normal hair follicle structure and skin health.

ACBP is crucial for healthy skin in mice.

Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.

Glioblastoma cells can make androgens, which might help the tumor grow.