Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that encapsulating coffee berry extract in nanoliposomes improved its stability, reduced toxicity, and enhanced its anti-aging effects on skin elasticity and lightening more than free extract.

This study suggests that 3,4,5-tri-O-caffeoylquinic acid activates β-catenin to enhance pigmentation in mouse hair follicles, human melanocytes, and melanoma cells during the hair cycle's growth phase.

In this study with organ-cultured human scalp hair follicles, high mTORC1 activity correlated with gray/white hair and reduced pigmentation, while inhibiting mTORC1 with rapamycin increased hair growth and pigmentation, suggesting mTORC1 inhibition could be a strategy for treating hair depigmentation and loss.

This review explores the factors contributing to premature graying of hair, highlighting the role of genetic and environmental influences such as oxidative stress, and discusses potential interventions like diet and herbal remedies, while noting the limitations of common treatments like hair dyes.

This study demonstrated that the biomimetic peptide PTP20 may help preserve hair pigmentation and reduce greying by enhancing melanocyte function and increasing melanin production in human hair follicles.

This study found that α-melanocyte-stimulating hormone increased melanin production in hair follicles of moulting Siberian hamsters, whereas [8-arginine]-vasotocin inhibited melanin production without affecting tyrosinase activity.

This study found that finasteride decreases melanin levels in melanocyte and melanoma cells by inhibiting MC1R, without causing cytotoxicity, suggesting its potential role in regulating melanogenesis.

This study found that rice bran ash extract and orthosilicic acid both increased melanin synthesis and related protein expression in melanocytes, suggesting potential therapeutic use for melanin deficiency.

Minoxidil does not specifically target any hair follicle cells.

This review examines the potential role of odorant receptors in human skin cells responding to flavor compounds and their implications for skin health and disease, without providing new clinical results.

GNPTAB gene is crucial for normal hair color in humans and mice.

This study found that non-pigmented hair follicles have significantly lower expression of nucleotide excision repair genes, which may be associated with reduced melanin production capacity in these follicles.

This study used ultrahigh-resolution optical coherence tomography to observe hair shaft structures, finding melanin granules absent only in white hair, which may explain color differences between black and white hair.

Laser hair removal might also work by damaging blood vessels around hair follicles.

This report documents follicular dysplasia with pigmentary changes in two adult cows, contributing to the understanding of this rare condition in cattle.

This case report describes three Iranian men with gradual reddish-brown pigmentation on their cheeks and preauricular areas since childhood, unresponsive to sunblocks and topical steroids.

This study found that Sox2 within dermal papilla cells in the hair follicle regulates hair pigmentation, influencing the type and production of melanin.

This study reviewed the effectiveness of long pulse 1,064-nm Nd:YAG laser treatments for leg veins, hair removal, and skin rejuvenation, highlighting its safety, particularly for darker skin types, due to reduced pigmentary side effect risks.

This review discusses the therapeutic use of photobiomodulation for various skin conditions, highlighting its efficacy in accelerating tissue repair, reducing inflammation, and treating pigmentary disorders and other skin diseases, but it reports no new clinical results.

This study examined skin biopsies from a woman with Addison disease and found melanocytic hyperpigmentation in the epidermis, with a notable melanocyte/keratinocyte ratio indicating increased melanocyte presence in the arm compared to the thigh.

This article reviews safe and effective hair removal options for dark-skinned patients and reports no new clinical results.

This study found significant structural and compositional differences in hair affected by alopecia areata compared to healthy hair, using a range of physico-chemical investigation methods.

This study found that pimecrolimus enhances melanin synthesis and promotes melanocyte migration, possibly by increasing MITF protein expression, which may explain its effectiveness in repigmenting vitiligo.

This study observed that the topical skin-whitening agent rhododendrol induced skin depigmentation in approximately 16,000 consumers, linked to melanocyte cytotoxicity and immune reactions.

This study suggests that hair loss in Chesapeake Bay retrievers is a breed-specific syndrome characterized by unique histological features and abnormal steroid production, possibly influenced by familial factors.

In this study, whole-genome sequencing of Lanping black-boned sheep identified ERBB4 and ROR1 genes as potentially important in their distinctive hyperpigmentation, enhancing understanding of their genetic evolution from Lanping normal sheep.

This review discusses factors influencing hair pigmentation and the etiology of canities, noting the lack of clarity in underlying mechanisms and calling for further research on treatment options.

This study found that a novel hydrogel scaffold, cGEL, significantly increased melanin production and melanotic gene expression in human melanocytes compared to other graft materials, suggesting its potential as a superior carrier for skin grafting.

In this study, the researchers optimized a method for culturing melanocyte precursors from hair follicles and found that 1,25-dihydroxyvitamin D3 significantly promotes their differentiation and melanin synthesis.

In this study, researchers found that cyclophosphamide treatment unexpectedly reduced splenic melanin deposition in a murine model, whereas this effect was down-regulated more by the normal and dystrophic catagen phase of the hair cycle.