66 citations,
July 2015 in “Journal of Molecular Biology” The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.
124 citations,
February 2018 in “Nature Reviews Genetics” Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.
111 citations,
January 2007 in “Seminars in cell & developmental biology” Hair, teeth, and mammary glands develop similarly at first but use different genes later.
13 citations,
May 2005 in “Seminars in Plastic Surgery” Follicular Cell Implantation might become a new treatment for hair loss and could lead to advances in organ regeneration.
60 citations,
July 2011 in “Stem Cells and Development” Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
49 citations,
August 2004 in “The FASEB Journal” Mice with human skin protein K8 had more skin problems and cancer.
28 citations,
October 2013 in “Cornea” Scientists have made progress in creating replacement teeth, hair, and glands that work, which could lead to new treatments for missing teeth, baldness, and dryness conditions.
21 citations,
October 2013 in “Molecular Biology of the Cell” The protein CCN2 controls hair growth by affecting hair follicle formation and stem cell activity in mice.
17 citations,
December 2001 in “Journal of Investigative Dermatology” The osteopontin gene is active in a specific part of rat hair follicles during a certain hair growth phase and might affect hair cycle and diseases.
8 citations,
June 2012 in “PloS one” Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.
98 citations,
February 2007 in “Seminars in Cell & Developmental Biology” Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.
69 citations,
August 1999 in “Developmental biology” The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.
48 citations,
June 2013 in “Journal of Dermatological Science” Valproic acid may help hair grow and could be a safe treatment for hair loss.
42 citations,
July 2014 in “Journal of biological chemistry/The Journal of biological chemistry” Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.
10 citations,
October 2020 in “Frontiers in Cell and Developmental Biology” Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.
7 citations,
September 2020 in “Frontiers in Cell and Developmental Biology” IL-36α helps grow new hair follicles and speeds up wound healing.
November 2023 in “npj regenerative medicine” Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.
610 citations,
April 2014 in “Nature Reviews Immunology” The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
160 citations,
January 2014 in “Seminars in cell & developmental biology” Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.
122 citations,
November 2010 in “Journal of Dermatological Science” Male pattern baldness involves hormones and cell signals affecting hair growth.
119 citations,
March 2020 in “Frontiers in Bioengineering and Biotechnology” Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.
101 citations,
January 1997 in “Journal of Investigative Dermatology Symposium Proceedings” Nerves and chemicals in the body can affect hair growth and loss.
89 citations,
September 2010 in “Annual Review of Genomics and Human Genetics” The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.
84 citations,
June 2013 in “Stem Cells Translational Medicine” New methods for skin and nerve regeneration can improve healing and feeling after burns.
82 citations,
March 2016 in “Cell” The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.
56 citations,
June 2015 in “Nature Protocols” Two-photon microscopy helps observe hair follicle stem cell behaviors in mice.
45 citations,
September 2012 in “Life Sciences” Aconiti Ciliare Tuber extract may help hair grow by activating a specific cell signaling pathway.
41 citations,
January 2007 in “Journal of Korean Medical Science” Minoxidil and ATRA together boost hair growth more effectively than minoxidil alone.
39 citations,
August 2016 in “Journal of Dermatological Treatment” Stem cell therapy may help treat tough hair loss cases.
30 citations,
January 2009 in “Nuclear Receptor Signaling” Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.