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Adding a second method to PROTACs could improve cancer treatment.

The book concludes that despite progress, cancer drug treatments have not met the expectations set in the 1960s and 1970s.

Alopecia areata can be an early sign of Hodgkin’s lymphoma and may improve with lymphoma treatment.

A new, efficient method has been developed to detect darolutamide and thalidomide, drugs used for certain hair loss and prostate cancer treatments, in pharmaceuticals and body fluids.

Certain medications, including some immune drugs, contraceptives, and hair loss treatments, are often linked to hair loss.

Oxidative stress is likely important in causing telogen effluvium, and antioxidants might help treat it.

Premature graying and hair changes can be treated with certain peptides and possibly targeting the endocannabinoid system.

Using existing drugs for new purposes could be a cost-effective way to treat chest pain and non-clogged heart arteries, with some drugs for lung blood pressure showing promise but needing more testing.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

The document provides detailed care instructions for elderly patients.

Pigmented papules on the ear can be a rare skin condition called cutaneous amyloidosis, treatable with topical tretinoin.

Kawasaki's disease can occur in adults and should be considered with specific symptoms and high ferritin levels.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Using the drugs AMD3100 and Tacrolimus together greatly improves skin healing and hair growth after a deep skin cut by increasing stem cells in the wound.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Myristoleic acid helps hair growth by boosting cell growth and recycling processes in hair follicle cells.

Piperine from black pepper can make hair less oily by blocking fat cell development in hair roots.

A specific hair protein variant increases the spread of breast cancer and is linked to worse survival rates.

Neuropathic pruritus is a commonly overlooked and wrongly diagnosed type of chronic itching that is hard to treat.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.

Androgenetic alopecia is a long-term, immune-related disorder that starts during puberty due to androgen secretion, and it might be improved with iron tablets, platelet transfusion, and anti-inflammation therapy.

Wigs greatly improve life quality for hair loss patients.

Activating NRF2 might help treat hair disorders by improving antioxidant defenses.

Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.

Minoxidil use can cause trichostasis spinulosa in long-term hair loss patients.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.