Minoxidil-Induced Trichostasis Spinulosa of Terminal Hair

December 2010 in “ Archives of Dermatology ”

Alexander A. Navarini, Maya Ziegler, Isabel Kolm, Lisa Weibel, Clarissa Huber, Ralph M. Trüeb

minoxidil trichostasis spinulosa female pattern hair loss follicular disorder keratinous sheath dilated follicle trichotrophic agent vellus hairs terminal hairs Rogaine

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The article reports a case of trichostasis spinulosa of the terminal hair type in a 35-year-old woman with female pattern hair loss who had been using topical minoxidil for 13 years. Trichostasis spinulosa is a follicular disorder resulting from the retention of numerous hairs surrounded by a keratinous sheath in a dilated follicle. The article emphasizes the importance of recognizing this disorder in patients with hair loss who have been using minoxidil for a long time. The case is unique because it was induced by minoxidil, a trichotrophic agent that transforms vellus hairs to terminal hairs.

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Research cited in this study

2 / 2 results

research Randomized Clinical Trial Comparing 5% and 1% Topical Minoxidil for the Treatment of Androgenetic Alopecia in Japanese Men

29 citations , July 2009 in “Journal of Dermatology”

This study confirmed that 5% topical minoxidil is more effective than 1% in increasing hair density in Japanese men with androgenetic alopecia, with no significant difference in adverse event rates.

research Trichostasis Spinulosa: Itchy Follicular Papules in Young Adults

27 citations , October 2002 in “International Journal of Dermatology”

This study presents a microscopic analysis of the pruritic variant of trichostasis spinulosa in two patients and reviews existing literature, reporting no new clinical results.