8 citations
,
January 2017 in “Journal of Cutaneous and Aesthetic Surgery” This study found that scalp micropigmentation provided moderate to great improvement in scalp coverage and patient satisfaction for those with hair loss, with any adverse effects being mild and temporary.
63 citations
,
May 2011 in “Clinical cancer research” In this study, topical CUR61414 was effective in inhibiting basal cell carcinomas in mice, but no clinical activity was observed in human trials.
7 citations
,
July 2013 in “Acta Biochimica Polonica” In this study, researchers found that cyclophosphamide treatment unexpectedly reduced splenic melanin deposition in a murine model, whereas this effect was down-regulated more by the normal and dystrophic catagen phase of the hair cycle.
August 2026 in “Cyprus Journal of Medical Sciences” This study evaluated a multimodal treatment involving iontophoresis-assisted growth factor delivery for hair loss, reporting significant reductions in daily hair shedding and high patient satisfaction, particularly in those with telogen effluvium; however, the design suggests these findings should be seen as preliminary.
13 citations
,
June 2020 in “Stem Cells International” In this study using a mouse model, ECM/SVF-CM, derived from adipose-derived stem cells, was observed to stimulate hair growth more effectively than SVF-CM by promoting cell proliferation, neovascularization, and anagen induction, which may support its potential as an improved treatment for hair loss.
June 2020 in “Journal of Investigative Dermatology” Hair shaft malformation contributes to Central Centrifugal Cicatricial Alopecia.
18 citations
,
September 2006 in “Dermatologic Surgery” This study reported that squamous cell carcinomas of the scalp can become extraordinarily aggressive, highlighting the need for early diagnosis and careful use of treatment strategies like wide excision and radiation therapy.
21 citations
,
November 2014 in “Journal of Endocrinological Investigation” This review discusses cross-sex hormone therapy for managing gender dysphoria in transsexual individuals and reports no new clinical results; it highlights the need for education and culturally sensitive training for healthcare professionals.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that targeting connective tissue sheath contraction with an MLCK inhibitor may improve hair growth in androgenetic alopecia by reducing premature hair regression caused by ectopic apoptosis of hair follicle progenitor cells.
1 citations
,
September 2025 in “Journal of Zhejiang University SCIENCE B” This abstract outlines the current understanding of cutaneous squamous cell carcinoma (cSCC), identifying it as the second most common non-melanoma skin cancer with risk factors like UV exposure and immunosuppression. It highlights cSCC's potential to metastasize and become fatal, affecting 2%-5% of in situ cases.
June 2025 in “British Journal of Dermatology” This study found that an ML model incorporating factors like Breslow thickness and age improved cutaneous malignant melanoma prognosis predictions compared to TNM staging, with a C-index of 80% versus 66.6% for TNM alone, suggesting ML's potential for personalized prognostication.
This review discusses Limbal Mesenchymal Stem Cell Secretome therapy for ocular chemical injuries, noting its potential in reducing inflammation and corneal opacity, but reports no new clinical results.
1 citations
,
January 2022 in “Oxidative Medicine and Cellular Longevity” This study found that hair follicle-derived mesenchymal stem cells can alleviate pyroptosis and improve ulcerative colitis symptoms in mice, suggesting potential new treatments for the condition.
June 2024 in “Journal of the Mississippi State Medical Association”
2 citations
,
November 1998 in “Journal of The European Academy of Dermatology and Venereology” This study focused on the ultrastructural and immunohistochemical aspects of dermal mast cells in systemic mastocytosis and their interaction with the epidermal melanin unit.
22 citations
,
March 2007 in “European journal of pediatrics” This study found that scanning electron microscopy revealed considerable abnormalities in hair morphology in MPS I, II, IIIA, and IIIB patients, potentially related to heparan sulfate accumulation.
31 citations
,
April 2016 in “Journal of the American Academy of Dermatology” Oral dexamethasone may help regrow hair in adults with alopecia totalis and universalis.
1 citations
,
December 2023 in “Cutis” This systematic review found that toluidine blue may be valuable for diagnosing and treating specific skin tumors in the context of Mohs micrographic surgery, though literature on its use is limited and mostly qualitative.
8 citations
,
February 2024 in “Matrix Biology”
3 citations
,
September 2022 in “Animal biotechnology” This study found that knocking down lncRNA MTC in Liaoning Cashmere goat skin fibroblasts inhibited cell proliferation and increased apoptosis, suggesting its role in facilitating cell growth by regulating specific proteins.
187 citations
,
April 2019 in “npj Regenerative Medicine” This study found that hMSC secretomes from umbilical cord Wharton's jelly had the most potent angiogenic effects, whereas those from adipose tissue demonstrated the weakest angiogenic potential.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that Quantitative Mass Spectrometry Imaging offers precise localization and quantification of active compounds in skin tissues, demonstrating benefits over traditional LC-MS in drug penetration studies.
18 citations
,
February 2001 in “Der Hautarzt” This case study of a 50-year-old woman with myotonic dystrophy and multiple basal cell carcinomas suggests there could be a genetic predisposition for certain cutaneous tumors in such patients.
2 citations
,
June 2025 in “Drug Testing and Analysis” This study found that after application of a testosterone cream containing 17α-methyltestosterone and testosterone propionate, these compounds could be detected in dried blood spots up to 97 hours post-application, potentially leading to sample contamination during fingertip puncture.
7 citations
,
December 2006 In this study, oral Tribulus terrestris extract significantly increased MSH expression in mouse hair follicle melanocytes, suggesting enhanced melanocyte activity and migration.
1 citations
,
August 2023 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics” This study developed a new method to analyze Cantú syndrome mutations in KATP channels, finding that while Kir6.1 mutations increase sensitivity to potassium channel openers, SUR2B mutations show reduced sensitivity, but both result in marked hyperpolarization compared to wild-type channels under basal conditions.
12 citations
,
February 2025 in “Scientific Reports” This study found that extracellular vesicles derived from mesenchymal stem cells and umbilical cord blood plasma enhanced wound healing and reduced scar formation in mice, suggesting their potential as therapeutic agents for skin repair.
September 2017 in “Current Issues in Pharmacy and Medical Sciences” This review discusses the use of mesenchymal stem cells in treating diseases, particularly focusing on their application in pediatric Graft-versus-Host Disease, with most studies reporting safety and effectiveness in animals.
1 citations
,
March 2023 in “Pharmaceutics” This study found that PBMCsec has anti-fibrotic effects on mouse and human skin scars by regulating pro-fibrotic gene expression and inhibiting myofibroblast differentiation and elastic fiber breakdown.
December 2024 in “Tropical Journal of Natural Product Research” This study observed that CTUMP's Herb shampoo significantly improved hair growth and density in mice compared to a saline solution, though it was less effective than minoxidil in promoting follicle development.