research Early Inductive Events in Ectodermal Appendage Morphogenesis
Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.
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research Resting No More: Redefining Telogen, the Maintenance Stage of the Hair Growth Cycle
The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.
research Genetic Basis of Skin Appendage Development
Hair, teeth, and mammary glands develop similarly at first but use different genes later.
research Turing Patterns in Development: What About the Horse Part?
Turing patterns are now recognized as important in developmental biology.
research Molecular Signaling in Feather Morphogenesis
Feather growth and regeneration involve complex patterns, stem cells, and evolutionary insights.
research TGF-β Family Signaling in Epithelial Differentiation and Epithelial-Mesenchymal Transition
The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
research Hardwiring Stem Cell Communication Through Tissue Structure
The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.
research From Neural Crest Cells to Melanocytes: Cellular Plasticity During Development and Beyond
Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.
research The Cycling Hair Follicle as an Ideal Systems Biology Research Model
The hair follicle is a great model for research to improve hair growth treatments.
research Molecular Genetic and Endocrine Mechanisms of Hair Growth
Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.
research Concise Review: The Plasticity of Stem Cell Niches: A General Property Behind Tissue Homeostasis and Repair
Stem cell niches are adaptable and key for tissue maintenance and repair.
research Module-Based Complexity Formation: Periodic Patterning in Feathers and Hairs
The conclusion is that understanding how feathers and hairs pattern can help in developing hair regeneration treatments.
research Live Imaging of Stem Cells: Answering Old Questions and Raising New Ones
Live imaging has advanced our understanding of stem cell behavior and raised new research questions.
research Perspectives on Hair Evolution Based on Comparative Studies on Vertebrate Cornification
Hair in mammals likely evolved from glandular structures, not scales.
research Platelet-Rich Plasma: History of Platelet Concentrates and Current Applications in Medicine
PRP helps heal and repair tissues in medicine but needs more research for better use.
research All Roads Lead to the Nucleus: Integration of Signaling, Transcription Factor-Mediated, and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration
The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
research Single Molecule FISH for Hedgehog Signaling in Mouse Skin
Hedgehog signaling controls hair follicle development and can affect skin cancer growth.
research Evo Devo of the Vertebrate Integument
The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.
research Regulation of Stem Cell Fate by HSPGs: Implication in Hair Follicle Cycling
HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.
research Non-Coding Double-Stranded RNA Induces Retinoic Acid Synthesis and Retinoid Signaling to Control Regeneration
Double-stranded RNA helps regenerate hair follicles by increasing retinoic acid production and signaling.
research Conversion of the Nipple to Hair-Bearing Epithelia by Lowering Bone Morphogenetic Protein Pathway Activity at the Dermal-Epidermal Interface
Blocking a specific protein signal can make hair grow on mouse nipples.
research Activin Controls Skin Morphogenesis and Wound Repair Predominantly via Stromal Cells and in a Concentration-Dependent Manner via Keratinocytes
Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.
research Hair Follicle Plasticity with Complemented Immune-Modulation Following Follicular Unit Extraction
Transplanted hair follicles can change and adapt to new areas of the body, with the immune system possibly playing a role in this adjustment.
research Stem Cells in the Skin
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
research A Systematic Summary of Survival and Death Signaling During the Life of Hair Follicle Stem Cells
The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
research Author Response: Lhx2 as a Progenitor-Intrinsic Modulator of Sonic Hedgehog Signaling During Early Retinal Neurogenesis
Lhx2 is a crucial regulator of the Sonic Hedgehog signaling in early mouse retinal development.
research Regeneration, Wound Healing, and Cancer
The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.
research Hypothesis: Wound-Induced TLR3 Activation Stimulates Endogenous Retinoic Acid Synthesis and Signalling During Regeneration
Activating TLR3 may help produce retinoic acid, important for tissue regeneration.
research Laminin-511 Is an Epithelial Message Promoting Dermal Papilla Development and Function During Early Hair Morphogenesis
Laminin-511 is crucial for early hair growth and maintaining important hair development signals.
research Conditional Activin Receptor Type 1B (Acvr1b) Knockout Mice Reveal Hair Loss Abnormality
Disrupting Acvr1b in mice causes severe hair loss and thicker skin.