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The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.

Tissue-specific variation in mutant load complicates genetic counseling and prenatal diagnosis.

A specific gene mutation causes hair loss and potential eye issues, even if vision seems normal.

Cyclodextrins improve finasteride's solubility and bioavailability for hair loss treatment.

The methylation of the HOXC8 gene's exon 1 affects cashmere fiber length in goats.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

Over 67 genes linked to ichthyosis help improve diagnosis and treatment.

BMP4 gene is crucial for hair follicle development in Liaoning cashmere goats.

Finasteride's molecular and crystal structures help develop new drug formulations.

New markers and pathways have been found in skin tumors, helping better understand and diagnose them.

The 3D structure of a key hair protein was modeled, revealing specific helical structures and stabilization features.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Electrostatic interactions mainly stabilize the binding of peptides to hair keratin.

Curcumin may help reverse aging by targeting specific genes.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

A family had a rare fungal infection called white piedra, identified as Trichosporon inkin.

New treatments for non-small cell lung cancer are being tested, with some already in use, focusing on immune response and targeting cancer cells, but side effects vary.

Researchers identified a new variant of the FGF5 gene in sheep that affects hair length.

Genetic factors affect hair loss, and molecular testing may help predict, diagnose, and treat it.

The research maps the complex development of early mouse skin, identifying diverse cell types and their roles in forming skin layers and structures.

HSP90 and lamin A/C are crucial for hair growth and could be targets for treating hair loss.

A new mutation in the hairless gene causes hair loss and skin wrinkling in mice.

Scientists have found specific genes linked to different hair loss conditions, which could lead to new treatments.

Changes in the HR gene have influenced hair growth and may lead to hair loss conditions in humans.

The compound 16 from the Merremia peltata plant could potentially be a good treatment for hair loss (alopecia) due to its strong activity and favorable skin absorption.

Analog 23 is a promising compound for prostate cancer treatment.

The study concluded that a protein important for hair strength is regulated by certain molecular processes and is affected by growth phases.

Merremia peltata leaf extract, particularly the bufotalinin compound, shows potential for treating hair loss.

Timosaponin BII, a plant extract, was found to promote hair growth in mice, similarly to minoxidil.