research Convergent Evolution of Cysteine-Rich Keratins in Hard Skin Appendages of Terrestrial Vertebrates
Cysteine-rich keratins evolved independently in mammals, reptiles, and birds for hard skin structures like hair, claws, and feathers.
Search
for
Sort by
Research
300-330 / 1000+ results 
research Skin Wound Healing in Humans and Mice: Challenges in Translational Research
The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.
research Biology of the Hair Follicle: The Basics
The document concludes that understanding hair follicle biology can lead to better hair loss treatments.
research Androgens and Alopecia
Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.
research Somatic Stem Cell Heterogeneity: Diversity in the Blood, Skin, and Intestinal Stem Cell Compartments
Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.
research Complex Hair Cycle Domain Patterns and Regenerative Hair Waves in Living Rodents
Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.
research From Telogen to Exogen: Mechanisms Underlying Formation and Subsequent Loss of the Hair Club Fiber
Hair shedding is an active process that could be targeted to treat hair loss.
research Plant Cell Culture as Emerging Technology for Production of Active Cosmetic Ingredients
Plant cell culture is a promising method for creating sustainable and high-quality cosmetic ingredients.
research Lineage Analysis of Epidermal Stem Cells
Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.
research A Discourse on Human Hair Fibers and Reflections on the Conservation of Drug Molecules
Hair analysis for drugs needs a better understanding of how drugs enter hair, considering factors like hair structure and pigmentation.
research Self-Organizing Hair Peg-Like Structures From Dissociated Skin Progenitor Cells: New Insights for Human Hair Follicle Organoid Engineering and Turing Patterning in an Asymmetric Morphogenetic Field
Researchers created early-stage hair-like structures from skin cells, showing how these cells can self-organize, but more is needed for complete hair growth.
research ILK Modulates Epithelial Polarity and Matrix Formation in Hair Follicles
ILK is essential for proper hair follicle development and structure.
research Nanocarrier Systems for Transdermal Drug Delivery
Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.
research Lipid Losses and Barrier Function Modifications of the Brown-to-White Hair Transition
White hair has less lipid content and absorbs water differently than brown hair.
research The Epithelial Stem Cell Niche in Skin
Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.
research Human Hair as a Testing Substrate in the Era of Precision Medicine: Potential Role of Omics-Based Approaches
Human hair shows promise for non-invasive medical testing, but more research is needed to standardize its use.
research Unlocking the Potential of the Secretome in Hair Growth Enhancement
Secretome-based therapies could improve hair growth better than current treatments.
research Irradiation-Induced Hair Graying in Mice: An Experimental Model to Evaluate the Effectiveness of Interventions Targeting Oxidative Stress, DNA Damage Prevention, and Cellular Senescence
Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.
research KIF18B Is a Cell-Type Specific Regulator of Spindle Orientation in the Epidermis
KIF18B is important for correctly positioning cell division machinery in skin cells, affecting hair follicle development.
research Modeling the Pharmacodynamics of Nandrolone Doping Drug and Implications for Anti-Doping Testing
The document concludes that finasteride can reduce nandrolone detection in doping tests, suggesting frequent testing and setting metabolite level thresholds for detection.
research EEMCO Guidance for the Assessment of Hair Shedding and Alopecia
The document explains hair growth and shedding, factors affecting it, and methods to evaluate hair loss, emphasizing the importance of skin biopsy for diagnosis.
research Advances in Understanding Hair Growth
Understanding glycans and enzymes that alter them is key to controlling hair growth.
research Expression and Functional Relevance of Melatonin Receptors in Hair Follicle Biology
Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.
research Epidermal Homeostasis: A Balancing Act of Stem Cells in the Skin
Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.
research Regenerating the Skin: A Task for the Heterogeneous Stem Cell Pool and Surrounding Niche
Different types of stem cells and their environments are key to skin repair and maintenance.
research Epidermal Development in Mammals: Key Regulators, Signals from Beneath, and Stem Cells
Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.
research Applications of Mesenchymal Stem Cells in Skin Regeneration and Rejuvenation
Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.
research Immune Deficiency-Related Enteropathy-Lymphocytopenia-Alopecia Syndrome Results from Tetratricopeptide Repeat Domain 7A Deficiency
A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.
research Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate
The extracellular matrix is crucial for controlling skin stem cell behavior and health.
research The Follicular Automaton Model: Effect of Stochasticity and Synchronization of Hair Cycles
The model showed that randomness accurately describes individual hair growth cycles and that synchronization can cause large fluctuations not seen in humans.