23 citations
,
November 2018 in “International Journal of Molecular Sciences” This study found that deoxyshikonin promoted wound healing in diabetic mice, suggesting it may contribute to wound repair in patients with diabetes.
6 citations
,
March 2022 in “Molecules” This study found that methyl jasmonate can induce tanshinone biosynthesis in S. miltiorrhiza by affecting the expression of the SmMEC gene, as supported by RT-PCR and transcriptomic data.
3 citations
,
August 2023 in “Biophysical Journal” In this study, researchers found that epithelial cells exhibit density-dependent metabolic heterogeneity, particularly in the pre-epithelial transition stage, where metabolic patterns correlate with cell proliferation and are influenced by actomyosin contractility.
3 citations
,
March 2012 in “Arab Journal of Urology” This study found that cromakalim and pinacidil significantly inhibited porcine detrusor muscle contractions, suggesting these ATP-sensitive potassium channel openers may have potential in treating certain bladder diseases.
3 citations
,
September 1980 in “Experientia” In this study, the pharmacological action of dobutamine on rabbit retinae was found to be distinct from that of other dopamine analogs like apomorphine and N-methyl-dopamine.
In this study, researchers used the CRISPR/Cas9 system to edit the FGF5 gene in Dorper sheep, observing increased density and finer wool, along with changes in cortisol levels and antioxidant enzyme activity linked to hair follicle development.
May 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that hair with lower levels of keratin associated proteins reduced the foreign body response in mouse subcutaneous implant tests compared to hair with higher keratin levels.
This review discusses the genetic differences between male and female pattern hair loss and highlights the uncertainty surrounding genetic factors in female pattern hair loss, but reports no clinical results.
43 citations
,
November 2012 in “Pharmaceutical research” This study found that fractional laser treatment significantly enhances the penetration and targeting of certain permeants, such as imiquimod and FD, to skin follicles, but not hydroquinone.
26 citations
,
March 2014 in “International journal of pharmaceutics” This study confirmed that the novel solid lipid microparticle formulation of adapalene demonstrated follicular penetration potential and targeted particle erosion in sebum in in vitro tests.
9 citations
,
January 2016 in “Journal of cosmetology & trichology” This article reviews the characteristics and distribution of alopecia areata and reports no new clinical results.
6 citations
,
July 2013 in “Experimental and Therapeutic Medicine” This study found that topical ginsenoside Rg1 may protect skin from UVB-induced damage in mice by reducing pathological changes and modulating cytokine mRNA expression associated with inflammation and immune response.
5 citations
,
January 2018 in “Annals of Dermatology” A 308 nm excimer laser successfully treated a boy with a rare skin condition after about a year of weekly sessions.
5 citations
,
March 2012 in “Microscopy Research and Technique” In this study, UVB exposure was found to alter certain chemical properties of the hair shaft, such as keratin components and water content, without significantly affecting its physical morphology.
3 citations
,
March 2019 in “Chinese Medical Journal” In this study using mice, fractional CO2 laser therapy promoted hair regrowth by inducing moderate inflammation, enhancing VEGF-mediated angiogenesis, and activating the Wnt10b signaling pathway.
2 citations
,
April 2025 in “Lasers in Medical Science” This study found that combining fractional CO₂ laser with halometasone cream improved chronic eczema more effectively than halometasone alone, with efficacy varying by laser parameters and showing better results at 4 weeks compared to 1 week. Pain was noted with higher energy treatments.
2 citations
,
January 2022 in “Lasers in Medical Science” This pilot study reported significant improvement in hair restoration and patient satisfaction with the use of fractional carbon dioxide laser followed by platelet-rich plasma, showing greater hair density increases using higher laser pulse energy settings in individuals with androgenetic alopecia.
This study found that radiofrequency microneedling significantly enhanced the absorption of topical triamcinolone acetonide, with insertion depth being more influential than RF energy levels.
January 2021 in “Advanced Biomedical Engineering” This study found that hair implant needles with longer point lengths and smaller bevel angles required less total work for insertion, which corresponded with surgeons' perceptions of insertion force differences.
January 2015 in “Przegla̧d dermatologiczny” This study evaluated 308 nm excimer light therapy for alopecia areata but the abstract does not provide specific clinical results or conclusions.
57 citations
,
December 2012 in “Molecules” This study found that mahanimbicine and a crude extract of Murraya koenigii may enhance wound healing in rats by promoting faster wound contraction and higher collagen deposition.
50 citations
,
December 2000 in “Journal of Pharmaceutical Sciences” This study found that electroosmotic flow through hair follicles significantly contributes to solution flow during iontophoresis in hairless mouse skin.
27 citations
,
January 2012 in “Current Topics in Microbiology and Immunology” This study found similarities in the regeneration processes of MRL mouse ears and axolotl limbs, involving G2 cell cycle arrest and nerve-dependent mitosis, but the role of p21 in axolotl limb regeneration remains uncertain.
25 citations
,
January 2017 in “Steroids” This study found that the progesterone metabolite 3α-THP increased the proliferation and gene expression of human glioblastoma cells, suggesting a role in tumor progression.
14 citations
,
July 2021 in “Biomedicines” This review discusses the roles of platelets in hemostasis and wound repair, the preparation methods for platelet concentrates, and their therapeutic applications in medicine and dentistry, reporting no new clinical results.
4 citations
,
February 2025 in “Pharmaceuticals” In this study, voglibose, commonly used for diabetes management, was found to reduce melanin synthesis and inhibit melanogenic signaling pathways in B16F10 melanoma cells, suggesting it could be repurposed for treating hyperpigmentation disorders with confirmed topical safety in human tests.
November 2025 in “Cosmetics” In this exploratory randomized controlled trial, participants using a combination of Centella asiatica-derived extracellular vesicles with recombinant growth factors showed significant improvements in hair thickness, density, length, and reduced hair loss and scalp sebum content after 56 days, compared to placebo.
October 2023 in “Journal of Drug Delivery Science and Technology” This review highlights the emerging potential of electrospun nanofibers in promoting hair growth for androgenetic alopecia, showcasing their advantages like high porosity and antibacterial activity, and the possibility of integrating active pharmaceuticals.
June 1999 in “Proceedings of SPIE” The study suggests that CO₂ laser creates hair transplant channels with significantly less lateral thermal damage than Ho:YAG laser in the human scalp.
June 2026 in “Mediterranean Journal of Hematology and Infectious Diseases” This case study reports a 15-year-old girl from a visceral leishmaniasis-endemic area in Greece presenting with various symptoms, including high fever, morning joint pain, and blood in urine, eventually leading to findings like rash, anemia, and kidney issues. Results are not detailed in this abstract.