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The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Preoperative pain assessment, regional anesthesia, and vitamin C can help prevent CRPS after surgery.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Jasmonic acid and its derivatives play important roles in plant health and have potential uses in medicine and agriculture.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Advanced human skin models improve drug development and could replace animal testing.

Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

Genetically modified plants could be an important source of omega-3 fats to meet global needs.

Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Thyrotropin-Releasing Hormone helps heal wounds in frog and human skin.

*Acorus calamus* has many medicinal benefits but needs more safety research.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.

Hormone treatments can help with women's skin and hair disorders, but they need careful monitoring and more research.

Cell aging can be both good and bad for tissue repair.

Sex hormones affect brain injury differently in males and females.