March 2025 in “Anatomy & Cell Biology” This study found that hair follicle stem cell-derived secretome mitigated cell death, apoptosis, and inflammation while upregulating neurotrophic factors in astrocytes exposed to oxygen-glucose deprivation, an in vitro ischemic stroke model, suggesting potential therapeutic benefits in stroke recovery.
January 2024 in “Scripta Medica” This review highlights the potential of nanoparticle delivery systems to mitigate doxorubicin's adverse effects and enhance its effectiveness, while discussing the integration of nanotechnology with Streptomyces-derived compounds to potentially advance future cancer therapies.
September 2023 in “Middle East Fertility Society Journal” This study found that nicotine may have a therapeutic role in mitigating the exacerbation of infertility conditions connected with alpha-synuclein-related Parkinson’s disease through molecular interactions identified via pathway analysis.
January 2023 in “Research Square (Research Square)” In this study, a high prevalence of Demodex mites was observed among workers in the mining, textile, and food factory industries, with textile workers showing the highest rates, although differences between groups were not statistically significant.
April 2020 in “The FASEB Journal” This study found that disrupting testosterone biosynthesis in male rats mitigated cardiovascular and autonomic impairments caused by endotoxemia, indicating testosterone's significant role in these conditions.
January 2020 in “한국미용학회지” This study found that incorporating Musa extracts in pretreatment products effectively mitigated hair damage during permanent wave application, closely maintaining hair thickness and tensile strength compared to untreated hair.
This study found that neonatal administration of Allopregnanolone may mitigate some behavioral effects of early maternal separation in adolescence, but also lead to similar adverse effects as the separation in adulthood.
January 2014 in “Dermatology Review” This review discusses the potential benefits of folate supplementation to mitigate methotrexate side effects in psoriasis patients and reports no new clinical data, suggesting further randomized controlled trials are needed.
August 2004 in “Veterinary Dermatology” This case report describes two guinea pigs infested with Acarus farris mites, which were successfully treated with Phoxim and removal of contaminated hay, leading to rapid resolution of skin lesions and alopecia.
January 1996 in “대한피부과학회지” This study found a significantly higher density of Demodex mites in sebaceous hyperplasia lesions compared to controls, suggesting a possible link between Demodex and the development of these skin lesions.
13 citations
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July 2024 in “Heart Failure Reviews” This review compiles data on how the apelinergic system may protect against heart damage caused by doxorubicin cancer treatment, suggesting its potential to mitigate cardiotoxicity, though further research in chronic models is needed to confirm these effects and mechanisms.
10 citations
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November 2022 in “International Journal of Cosmetic Science” In this laboratory study, Camellia japonica fruit shell extract showed potential to mitigate hair loss by promoting hair cell growth and reducing harmful effects of DHT and oxidative stress.
9 citations
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March 2022 in “Journal of Chemical Information and Modeling” This study identified a series of novel β-glucuronidase inhibitors that may help mitigate adverse effects of first-line anti-cancer drugs by targeting gut bacteria, based on virtual high-throughput screening findings.
This study observed that methylene blue, a mitochondrial-targeted antioxidant, promotes hair follicle stem cell proliferation and viability through reduced oxidative stress and enhanced β-catenin signaling, and it may also protect against hair loss related to glucagon-like peptide-1 receptor agonists by reducing metabolic stress.
December 2025 in “Chemical Biology & Drug Design” This study suggests that hesperidin may regulate pathways in hair follicle cells to help mitigate hair loss, revealing molecular mechanisms of nitric oxide donor-mediated hair follicle protection.
October 2025 in “Dermatology Practical & Conceptual” This source highlights the potential benefits of identifying risk factors and intervening early to mitigate acne scarring and improve quality of life. It also emphasizes the importance of recognizing acne severity predictors to guide preventive strategies and optimize patient outcomes.
April 2025 in “Journal of Investigative Dermatology” This study discovered that exosomes from adipose-derived mesenchymal stem cells can mitigate damage in dermal papilla cells by modulating the TGF-β1/SMAD2 signaling pathway through miRNAs miR-574-3p and miR-125a-5p, revealing potential therapeutic targets for androgenetic alopecia.
February 2025 in “Buletin Veteriner Udayana” In this study, therapy successfully resolved mite infections in a domestic cat, leading to improved skin and ear health, including reduced crusting and itchiness, and cleaner ears after 15 days.
January 2023 in “Revista Brasileira de Parasitologia Veterinária/Brazilian Journal of Veterinary Parasitology” This study found that a single topical dose of fluralaner effectively eliminated Lynxacarus radovskyi mites from naturally infested domestic cats within 42 days, with treated cats remaining mite-free until day 98, unlike the untreated control group which continued to test positive.
December 2022 in “Otorhinolaryngology, Head and Neck Pathology.” This study found that applying photobiomodulation therapy after septoplasty helped reduce pain and mitigate changes in the autonomic nervous system compared to those who did not receive the therapy.
April 2022 in “Anti-cancer agents in medicinal chemistry” In this literature review, researchers compiled evidence on repurposed synthetic radioprotective agents, including metformin and simvastatin, that have demonstrated potential in mitigating the side effects of radiotherapy in cancer treatment.
December 2021 in “Pathologica” This case report describes a rare instance of trichogerminoma with unusually numerous mitotic figures and a higher Ki67 proliferative rate, distinguishing it from previously documented cases.
January 2023 in “Cutaneous and Ocular Toxicology” This study found that ATP may help reduce ribociclib-induced skin damage in rats by mitigating biochemical changes associated with oxidative stress.
104 citations
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January 2014 in “Journal of Clinical and Experimental Dentistry” This review outlines the oral toxic effects of chemotherapy and stresses the need for evaluating dental health prior to treatment to mitigate these complications, but it reports no new clinical results.
96 citations
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January 1997 in “Clinics in Dermatology” This study found that G protein-coupled estrogen receptor enhances melanin synthesis in melanoma cells through cAMP-PKA-MITF-TYR signaling, suggesting its potential as a drug target for chloasma treatment.
24 citations
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October 2012 in “The International Journal of Biochemistry & Cell Biology” In this study, testosterone protected female embryonic heart cells from metabolic stress by being converted into metabolites that activate estrogen receptors and up-regulate certain mitochondrial channel proteins.
22 citations
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July 2024 in “Archives of Plastic Surgery” This review detailed the types and mechanisms of injectable "skin boosters" and evaluated their effectiveness and safety for mitigating age-related skin changes, providing insight into their use in contemporary dermatological practice.
19 citations
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September 1995 in “Food and nutrition bulletin” This article reviews the toxic effects of mimosine in Leucaena leucocephala and discusses various methods to mitigate its toxicity but presents no new findings.
15 citations
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October 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that erlotinib exacerbates inflammation in a mouse model of skin disease and that IL-1 inhibition could mitigate skin-related side effects of EGFR inhibitors.
13 citations
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January 2002 in “Clinics in dermatology” This study found that AHCC supplementation significantly reduced alopecia severity in Ara-C treated rats and mitigated liver injury-related side effects in mice treated with 6-MP and MTX.