Original Article: Detection and Histopathological Findings of Demodex Folliculorum in Sebaceous Hyperplasia
January 1996
in “
대한피부과학회지
”
Studysummary This study found a significantly higher density of Demodex mites in sebaceous hyperplasia lesions compared to controls, suggesting a possible link between Demodex and the development of these skin lesions.
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The study investigated the presence and density of Demodex folliculorum in sebaceous hyperplasia (SH) compared to a control group. It involved 11 patients with SH and 40 controls, with excision biopsies performed on 8 SH patients. Results showed a significantly higher prevalence and density of Demodex in SH patients (100% prevalence, mean density of 28.9/lesion) compared to controls (85% prevalence, mean density of 2.1/follicle). Histopathological findings in SH included abnormal keratinization, follicular plugging, and inflammatory infiltration. The study suggested a possible relationship between high Demodex density and the development of SH skin lesions.
