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This study demonstrated that in live rodents, actin filaments adjust their structure to facilitate membrane transfer between cellular compartments with different biophysical properties.

In this study, researchers found that in hairy guinea pig skin, minoxidil delivered via 40-nm nanoparticles had higher skin penetration than 130-nm nanoparticles, indicating nanoparticle size affects permeation.

This article discusses the potential of novel microneedle transdermal systems for enhanced drug and vaccine delivery through the skin, but reports no clinical results and emphasizes ongoing trials.

This review discusses the advancements and applications of multiphoton microscopy in dermatology, including its role in imaging skin disease and drug transport, and reports no new clinical results.

In this paper, the authors describe a standardized micrografting technique for hair transplantation that significantly speeds up the procedure and minimizes surgical trauma, enhancing graft survival.

This review explores the development and cosmeceutical applications of microneedles for skin treatment, without reporting new clinical results, emphasizing safety and public perception as key factors for commercialization.

This study found that medium-sized particles (643 and 646 nm) penetrated deeper into porcine hair follicles in vitro than smaller or larger particles, suggesting size-selective targeting within follicular sites.

This preclinical study found that a machine-learning-driven strategy for fabricating microneedles with optimal hardness and rapid dissolution significantly promoted hair regrowth in androgenetic alopecia mice by activating the Wnt/β-catenin pathway, surpassing the effects of minoxidil.

This study developed a new mask-free method using digital micromirror and microfluidic systems to create multicellular heterospheroids for drug screening, finding that heterospheroids exhibit higher drug resistance and combinatorial drugs are more effective than single drugs in cancer therapeutic applications.

This study observed that smaller polymeric submicron particles provided more efficient selective drug delivery to inflamed skin in a mouse model, enhancing therapeutic effects while reducing systemic adverse effects.

This review discusses 3D printing developments in topical delivery systems, highlighting the potential for 3D printed microneedles to become prominent in personalized cosmetic applications, but reports no new experimental results.

In this study, the researchers developed minoxidil cubosomes using nanotechnology, which improved drug penetration in the skin, showed greater hair growth efficacy, and reduced adverse skin reactions compared to traditional minoxidil solutions.

This study developed a microdroplet technology to produce cell microspheres that successfully induced hair follicle regeneration in a mouse model, suggesting potential improvements in hair loss treatments.

In this study, mini rats with reduced growth hormone and insulin-like growth factor-1 levels exhibited distinct differences in skin thickness and hair cycle compared to standard Wistar rats, suggesting potential use as an animal model for studying GH deficiency-related skin conditions.

This article presents a protocol for using mouse tail skin to study hair follicle stem cells, enabling visualization of calcium signaling and other cellular features in various conditions but reports no new research data.

This study used confocal Brillouin microscopy to observe that a decrease in tissue compressibility occurs during the development and regeneration of axolotl limbs, suggesting mechanical changes linked to regeneration stages undetectable by fluorescence microscopy.

The document describes a method for preparing hair for microscopy by embedding it in plastic, cutting it, and storing it cold before imaging.

This study demonstrated that using morphometric and 3D reconstruction software to evaluate scalp biopsies in non-cicatricial alopecias may be feasible and sensitive for detecting subtle follicular changes.

In this study, researchers identified the miR-22-3p/CLIC4 signaling pathway as a key regulator in hair follicle miniaturization among androgenetic alopecia models, suggesting that targeting CLIC4-mediated sonic hedgehog pathway disruption may offer new therapeutic strategies for AGA treatment.

This study found that smaller mesoporous silica particles (400-600 nm) accumulated in skin furrows, suggesting their potential as carriers for enhancing the delivery of topical medications like metronidazole.

This study found that patients experienced less pain when using a 1-mL syringe compared to a 3-mL syringe, despite both having the same needle size.

TrichoScan effectively measures hair growth improvements in people using minoxidil.

This source highlights that fractional CO2 laser, as a minimally invasive technology, shows significant benefits in treating various skin and mucosal conditions by improving therapeutic outcomes, shortening recovery times, and enhancing precise personalized interventions through emerging technologies like AI and biomarker monitoring.

In this study, N-MXD (minoxidil nanoparticles) was shown to deliver more drug into hair bulbs and enhance IGF-1 and VEGF levels more effectively than commercial formulations, resulting in higher therapeutic efficiency for hair growth in C57BL/6 mice.

This study demonstrates that the newly developed portable reflectance confocal microscope (PRCM) offers real-time, noninvasive monitoring of wound healing processes by visualizing skin morphology in both mice and humans.

This study discusses the expanding use of microneedles beyond transdermal drug delivery, highlighting recent advancements for treating hair loss, eye diseases, and oral disorders, while emphasizing future challenges in generalizing this technology.

This study introduces the PRECISE scale, a quantitative tool to classify androgenetic alopecia, aiming to improve planning and outcomes for hair transplantation surgeries by evaluating the whole hairless and thinning areas.