Age-Related Changes in the Dorsal Skin Histology in Mini and Wistar Rats

    April 2002 in “ PubMed
    Aya Ikawa, Yoshiyuki Ishii, Kazuhiko Suzuki … Kazuteru Doi
    Studysummary In this study, mini rats with reduced growth hormone and insulin-like growth factor-1 levels exhibited distinct differences in skin thickness and hair cycle compared to standard Wistar rats, suggesting potential use as an animal model for studying GH deficiency-related skin conditions.
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    Research cited in this study 3

    1. The Chemotactic Effect of a Dermal Papilla Cell-Derived Factor on Outer Root Sheath Cells Journal of Dermatological Science · 2001
    2. Insulin-Like Growth Factor 1 and Hair Growth Dermatology Online Journal · 1999
    3. Cells Within the Bulge Region of Mouse Hair Follicle Transiently Proliferate During Early Anagen: Heterogeneity and Functional Differences of Various Hair Cycles Differentiation · 1994