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Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.

This study found that targeting SV40 T antigen expression to hair follicles in transgenic mice caused abnormal hair structure and hair loss, but did not lead to cell immortalization or tumor formation in follicles.

This study found that combining platelet-rich plasma therapy with minoxidil was more effective in treating androgenetic alopecia in men than either treatment alone.

This study found that FGF5-/- rabbits exhibited a significant long hair phenotype by prolonging the anagen phase, suggesting FGF5 acts as a negative regulator of hair growth.

This review discusses various applications of CRISPR-based tools in cancer research, emphasizing their potential for investigating microRNA functions and developing microRNA-based therapies, despite challenges like off-target effects and delivery issues in using CRISPR/Cas9.

This study demonstrates that Rac1 activity is essential for normal hair follicle formation but influences hair structure and pigmentation, in terminal differentiation, through alterations in hair shaft, cuticle, and pigmentation organization.

This review discusses the potential of follicular drug delivery systems to target the pilosebaceous unit and reports no new research findings.

In this study, intradermal injections of 0.5% minoxidil significantly improved hair growth and volume in women with female androgenetic alopecia compared to a placebo, with a good safety profile reported.

In this study, researchers found that pigs with genetically disrupted ANTXR1 were resistant to Senecavirus A infection, showing no clinical symptoms, and provided a model for human GAPO syndrome, while confirming ANTXR1 as a receptor for the virus.

This review summarizes recent therapeutic advancements in treating various forms of alopecia, including new applications of oral minoxidil, dutasteride, finasteride, Janus kinase inhibitors, and novel hair transplant techniques, without presenting original research results.

This abstract does not provide research results or a summary of findings, but only lists author affiliations and contact information.

This study found that transthyretin and megalin expression in human scalp hair follicles varies significantly with the hair growth cycle, peaking during anagen and diminishing in catagen and telogen phases.

This review provides a comprehensive overview of multidisciplinary dermo-aesthetic interventions for breast cancer patients, aiming to establish safe protocols involving various specialists to improve quality of life, although consultation with an oncologist before treatment is advised.

This study found that oral dutasteride increased hair count more than intralesional administration in androgenetic alopecia, but more research is needed for a reliable comparison.

In this study, finasteride-treated WAG/Rij rats showed a significant increase in spike-wave discharges when administered endogenous steroids THPROG and THDOC, indicating potential exacerbation of absence seizures.

In this study, PRP was found to show promise in treating melasma, offering consistent positive outcomes and satisfaction rates among patients, especially when combined with treatments like hydroquinone and tranexamic acid, though further research is needed to confirm long-term efficacy and safety.

This study found that treating androgenetic alopecia with platelet rich plasma increased hair density and diameter while decreasing the proportion of telogen and vellus hairs.

This study observed that among dermatologists in Spain, topical minoxidil and oral finasteride are the most commonly prescribed treatments for male androgenic alopecia, while oral dutasteride and oral minoxidil have seen increased use in recent years.

This review discusses the use of mesotherapy, highlighting its popularity and the lack of large, randomized controlled trials, and advises cautious use.

This study found that stem cells can temporarily act as non-professional phagocytes during hair cycle regeneration by clearing apoptotic cells through a process requiring local lipids and retinoids for activation, providing insights into their dual role in maintaining tissue integrity.

Among families with pediatric brain disease, this study identified over 200 novel genetic causes, revealing potential treatment points using drug repurposing or nutritional supplementation.

This study found that neonatal administration of finasteride affected adult learning and memory in rats, enhancing object recognition but impairing aversive learning, with no effect on anxiety-like behavior.

This study suggests that AT-ASCs significantly improve terminal and intermediate hair counts and hair caliber in androgenetic alopecia more than PRP, though with more side effects like headache and erythema.

This review discusses various nanocarriers for gene and genome editing therapies, highlighting that ionizable lipid nanoparticles show advanced delivery performance, while emerging polymer-based and exosome-inspired carriers are rapidly advancing for targeted applications.

This study found that centrosome ablation in developing epidermis triggers cell surveillance pathways, resulting in thinner skin and halted hair follicle growth, while later stages of epidermal growth may operate independently of basal progenitor division orientation.

This study found that BOTOX doses of 75–100 U effectively reduce postvoiding residual urine and detrusor pressure in patients with detrusor sphincter dyssynergia.

Stem cell research and regenerative medicine have made significant advancements in treating various diseases and conditions.

In this study, researchers overexpressed Lrig3 in mouse skin and observed hair loss linked to changes in skin protein profiles and signaling pathways, suggesting a potential role for Lrig3 in maintaining skin homeostasis.

This thesis review found that invasive methods like PRP and hair transplantation can significantly improve hair quality and density in androgenetic alopecia, though effectiveness and safety vary by technique.

This review reports that while platelet-rich plasma shows promise as a safe treatment for various types of hair loss, variability in studies limits definitive conclusions on its effectiveness.