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In this study, the Peninsula Timerevert Needle was found to provide effective treatment for skin photoaging and acne scars with less pain and shorter treatment duration compared to EndyMed, although it caused more bleeding.

This study demonstrates that machine learning-assisted fabrication of PRP-incorporated microneedles effectively promotes hair regrowth in AGA mice, outperforming minoxidil and mitigating biosafety risks associated with synthetic materials.

This study achieved a first by successfully forming large quantities of dermal papilla spheroidal microtissues, which retained their hair induction potential, using a micropatterned culture system.

This study found that a machine-learning-driven strategy helped develop microneedles with high hardness and rapid dissolution, effectively promoting hair regrowth in androgenetic alopecia mice by activating the Wnt/β-catenin pathway, surpassing minoxidil's effects without biosafety risks.

This study found that gentamicin-loaded exosomes derived from bovine leukocyte spleen extract enhanced antimicrobial activity and promoted tissue regeneration in infected diabetic mouse wounds, suggesting a potential innovative therapeutic strategy for diabetic foot ulcers by combining infection control with pro-regenerative and immunomodulatory effects.

This study describes an analytical technique combining field-enhanced sample stacking with dispersive liquid-liquid microextraction, offering improved sensitivity for detecting finasteride and its metabolite in urine samples from patients treated for androgenetic alopecia.

This review examines various methods for purifying extracellular vesicles loaded with drugs, highlighting their principles, benefits, and drawbacks, and stresses the importance of standardized guidelines to enhance the reproducibility of EV-based drug delivery research.

This study investigated the use of 3D cell culture technology to explore hair follicle regeneration, examining the impact of the 3D cellular environment on hair follicle morphogenesis and the effects of microwell depth on spheroid formation.

This review study found that vesicular carriers like liposomes, niosomes, invasomes, and transferosomes can enhance drug penetration through follicles, benefiting treatments for alopecia, acne, and infections, as well as potentially facilitating systemic delivery of antihypertensive drugs and insulin.

In a murine burn wound model, this study found that an enhanced fractal self-pumping dressing significantly reduced wound area and tissue edema by efficiently draining excess exudates.

This study found that finasteride- and minoxidil-loaded nanoparticles in a gel improved skin permeability and drug retention, suggesting a promising approach for topical alopecia treatment with reduced dosing frequency and side effects.

This study found that infiltrating dilute adrenaline into the recipient area during implanter-based FUE hair transplantation significantly reduced intraoperative bleeding, improving graft precision and visualization, without major safety concerns among the 50 patients observed.

This study found that Soluplus and L-ascorbyl 2,6-dipalmitate nanoparticles may improve minoxidil's skin permeability through stable hydrophobic interactions, enhancing its potential for targeted skin application.

This scoping review explores devices that mechanically process lipoaspirate for cell-based therapies but finds insufficient evidence to determine their clinical effectiveness due to lack of standardization and data variability.

This study found that combining weekly transverse needling sessions with mini-punch grafting significantly accelerated and enhanced repigmentation in stable, resistant non-segmental vitiligo lesions compared to each procedure alone or non-procedural treatment.

In this study, a peptide hydrogel scaffold loaded with umbilical cord-derived mesenchymal stem cells was used to repair damaged endometrium in rats, significantly improving fertility and live birth rates by restoring endometrial thickness and promoting angiogenesis.

This study used digital-light-processing bioprinting to create a 3D skin-on-a-chip model with a miniaturized vascular network to closely study immune cell interactions similar to real human skin, demonstrating the potential to analyze immune-T cell trafficking influenced by skin signals.

This protocol describes a method for cultivating stem cells on a fibrin carrier for potential transplantation to the eye, but it reports no new clinical findings.

This study found that combining fractional radiofrequency microneedling with 5% topical minoxidil improved hair count and thickness more than minoxidil alone in Chinese men with male pattern hair loss.

Micrografts are useful for healing wounds, regenerating bone and periodontal tissues, and improving hair transplantation outcomes.

A new microneedle system effectively delivers finasteride to treat hair loss.

This study found that a microneedle array patch using a blend of kangfuxin, chitosan, and fucoidan significantly accelerated wound healing in rats by enhancing epithelial thickness and collagen deposition.

This study demonstrated that combining amorphization and nanonization of drugs enhances both saturation solubility and dissolution rate, potentially offering therapeutic benefits for formulations like dermal applications.

In this laboratory study, a novel minoxidil-loaded microneedle patch demonstrated potential for treating alopecia areata by promoting slow drug release and reducing application frequency, while exhibiting antibacterial properties to prevent infection during use.

This study introduces a five-modal microscopy technique that allows label-free, in vivo observation and quantitative analysis of various wound healing processes.

This study demonstrated that combining cell conditioning with mild protease digestion enhanced the visualization of versican mRNA in formalin-fixed mouse skin tissue sections compared to using either technique alone.

This study presents a novel composite hydrogel dressing with berberine-loaded silk fibroin microspheres and Calotropis gigantea fibers, demonstrating enhanced antibacterial activity, mechanical strength, and wound healing capabilities in treating chronic and infected wounds.

This review discusses the mechanisms and engineering techniques for enhancing the targeted delivery of extracellular vesicles in therapies but reports no new clinical findings; the authors encourage further exploration to advance clinical applications.

This study found that pen-type microwells enhanced hair follicle germ formation by promoting cell assembly, suggesting microwell array geometry significantly influences in vitro hair follicle development.