Machine Learning-Driven Optimization of Therapeutic Substance Composition for High-Hardness, Fast-Dissolving Microneedles for Androgenetic Alopecia Treatment

    August 2025 in “ PubMed
    Peiyu Yan, Jing Sun, Yuehua Zhao, Wei Deng, Miaomiao Zhang, Yang Li, Xiangru Chen, Ming Hu, Jilin Tang, Dapeng Wang
    From the encyclopedia
    Platelet-Rich Plasma →

    growth factors taken from your blood and injected into your scalp to stimulate hair

    Minoxidil →

    An essential vasodilator with some anti-androgenic effects

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    Studysummary This study found that a machine-learning-driven strategy helped develop microneedles with high hardness and rapid dissolution, effectively promoting hair regrowth in androgenetic alopecia mice by activating the Wnt/β-catenin pathway, surpassing minoxidil's effects without biosafety risks.
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