Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study demonstrated that a new biomimetic tissue engineering strategy using DP spheroids with vascularization significantly restored the hair-inducing properties of dermal papilla cells compared to traditional 3D cultures.

This case study indicates that older patients with NMOSD may show favorable clinical improvements with aggressive treatment, even when the intervention is initiated later in the disease course.

This study used atomic force microscopy to image surface structures of human epidermal melanocytes, hair follicle amelanotic melanocytes, and mouse melanoma cells, revealing differences in branch structure and granule distribution.

This study highlights fat grafting and nanofat as promising options for treating dark circles, offering benefits in improving both volume and skin quality through a single-stage procedure with long-lasting outcomes.

This study found that in superficial angiomyxomas, S100A4-positive mesenchymal niches may induce non-neoplastic adnexal epithelial growth, and highlighted evidence of mesenchymal-to-epithelial transition in eccrine duct branching, especially in Carney's complex cases.

This study found that certain circulating miRNAs in skin and plasma may serve as potential biomarkers for distinguishing frontal fibrosing alopecia from control cases, highlighting the need for further validation in larger cohorts.

This study revisits and reproduces Felix Pinkus' concept of the vitreous membrane in hair follicles, suggesting these structures may play a role in differentiation or nutrition due to their location in metabolically dynamic regions.

This study found that GPC1 plays a crucial role in regulating angiogenesis in human dermal microvascular endothelial cells, which may make it a potential target in alopecia treatment research.

In this study, researchers found that the interaction between dermal papilla and endothelial cells decreases with age, affecting signaling pathways that promote hair regeneration and angiogenesis in mouse models.

This study developed microfluidics-based 3D microtumors to model minimal residual disease in ovarian cancer, highlighting their alignment with patient-derived MRD and response to a fatty acid oxidation inhibitor.

This study found that combining hair follicle-derived smooth muscle cells with a natural biomaterial created vascular constructs with mechanical and functional properties similar to native arteries, suggesting potential for arterial implantation.

Results are not reported in this abstract, which describes a man in his 30s with a 4-year history of patchy hair loss on the right lower leg and associated itching, highlighting the use of dermoscopy in his examination.

This article reviews the indications for micropigmentation in dermatological conditions like stable vitiligo and alopecia, but presents no new clinical results.

Minoxidil affects rat fluid dynamics, altering pressure and circulation, improving blood flow and hair growth.

This study found that hypoxic preconditioning of nanofat from donor mice reduced its vascularization capacity in vivo, suggesting that this approach cannot currently enhance nanofat's regenerative potential.

This study found that human epidermal stem cells can adapt to small temperature variations via mTOR signaling, and that prolonged mTORC1 inhibition supports stem cell maintenance.

This study developed 3D micropatterns with magnesium silicate nanospheres that mimic vessels and hair follicles for potential use in skin regeneration by reconstructing vasculature and promoting hair growth.

This study explored the use of "microfollicles," a human hair follicle organoid model, as an in vitro tool for testing hair-growth substances, finding up to 75% overlap in gene expression changes with human clinical biopsy responses to minoxidil, indicating its potential for pre-clinical substance testing.

This study found that the CD301b-expressing subpopulation of macrophages plays a crucial role in promoting reparative processes during the mid-stage of skin wound healing in a mouse model.

Mast cells may significantly contribute to central centrifugal cicatricial alopecia.

In this study, particles similar in size to keratin cells were surprisingly found to penetrate more efficiently into hair follicles due to a possible pumping effect from moving hairs.

This review discusses the use of microemulsions for transdermal drug delivery and emphasizes the importance of component selection for enhancing drug permeation and skin tolerance, without reporting new clinical results.

This article, a special issue on hair follicle biology and pathology, reports no new research findings.

In this study, reflectance confocal microscopy was used to diagnose periorificial dermatitis, revealing specific skin changes such as hair follicle dilatation, increased vascular density, and inflammation, which help distinguish it from similar conditions.

This study investigated the heterogeneity of CD34+ cells in wound healing, identifying distinct cell clusters and suggesting potential therapeutic approaches for anagen and diabetic wounds.

Minoxidil improves blood flow in heart failure patients.

This paper explores the relationship between the dermal extracellular matrix and cutaneous malignant melanoma, suggesting that ECM involvement may play a key role in the cancer's growth, invasiveness, and initial metastasis.

This study identified that bone marrow-derived CD34⁺ cells act as fibroblast progenitors to enhance tissue regeneration in ischemic limbs by promoting angiogenesis through interactions with macrophages.