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This study found that implanting hair-follicle-associated pluripotent stem cell sheets in mice significantly accelerated wound closure and reduced scar formation compared to non-implanted controls.

This study found that Eucommia ulmoides bark extract shows potential antioxidant and hair follicle-support properties in vitro and in vivo, but further validation is needed to confirm these effects.

This study suggests that vellus to terminal hair follicle reconversion can occur in male pattern androgenetic alopecia using an in vivo model with minoxidil and platelet-rich plasma treatment.

In an animal study, researchers observed that a newly synthesized deoxycholic acid derivative showed similar prostate protection effects to finasteride in Wistar rats while being less toxic.

This review assessed experimental studies on herbs used for alopecia, identifying potential mechanisms involving hair cycle management and keratinocyte processes, but highlighted a need for improved evidence on quality control and toxicity of these herbal treatments.

This study found that Samhwang-Sasimtang herbal extract may enhance hair growth in mice, as indicated by increased hair follicle activity and reduced growth inhibition factors compared to a control.

This study found that combining oral herbal composition with topical hair tonic in mice resulted in enhanced hair growth, improved blood antioxidant capacity, and reduced lipid peroxidation and triglyceride levels.

This research explored hair loss and regrowth, highlighting the use of animal models like mice and rats to better understand hair physiology, shedding cycles, and potential treatments, with implications for human application.

This review discusses the limitations of animal models, particularly mice, in accurately predicting human skin wound healing outcomes and emphasizes understanding species-specific differences in skin characteristics for better translation to clinical settings.

This review discusses the use of the human-on-mouse xenograft model for studying the human hair follicle cycle and emphasizes its utility for pharmacological testing, without reporting new clinical results.

In this study, in vitro and in vivo models showed that chrysin enhanced the efficacy of docetaxel and reduced its adverse effects in non–small cell lung cancer treatment.

This study found that KLF4 expression in mouse hair follicle stem cells is important for effective cutaneous wound healing, with its knockdown leading to reduced stem cell populations and delayed healing.

In this study, Wharton’s Jelly Mesenchymal Stem Cells, cultured with human platelet lysate, showed enhanced wound-healing capabilities and multilineage differentiation potential, distinguishing them from bone marrow-derived stem cells and presenting exciting prospects for regenerative medicine.

This study reports that hair follicle-derived mesenchymal stem cells significantly reduced hair loss and inflammation in alopecia areata models, suggesting a potential therapeutic approach.

This study suggests that Merkel cell polyomavirus T antigen-positive cells resembling Merkel cell carcinoma may originate from epithelial cells in human hair follicles, potentially informing future transgenic mouse models for this cancer.

Apremilast may help treat hair loss in alopecia areata.

This study demonstrates that mouse eyelashes can effectively model human eyelash growth to analyze morphology, development, and the effects of growth-stimulatory agents like bimatoprost.

Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.

This study found that in a shaving animal model of mice, increased enzyme activities and gene expression correlated with enhanced hair growth, suggesting they are good biomarkers in the anagen phase.

This study presents a new mouse model for investigating chronic graft-versus-host disease, highlighting the role of human thymic tissue in developing multiorgan fibrosis driven by human immune cells.

In this study, researchers reported that the activation of EDA2R by p53 leads to p53-dependent cell death in cancer cells and is involved in chemotherapy-induced hair loss.

Specific immune cells cause alopecia areata and blocking certain proteins can prevent it.

This study concluded that rapid thawing during cryoablation enhances neutrophil and lymphocyte infiltration, increases oxidative stress, and induces cell death, resulting in more substantial tissue damage in mice compared to natural thawing.

This study in transgenic mice found that the combination of SPF 15 sunscreen and a UVA filter provided strong protection against UVA-induced elastin promoter activation and thus may reduce photoaging.

This review discusses recent advances in understanding the pathogenesis of autoimmune alopecia areata and reports no new clinical results; it highlights potential for developing more effective treatments.

This study developed a humanized scalp model in mice which demonstrated that transplanted cultured human hair follicle dermal cells contributed to the restoration of damaged hair follicles.

This study found that applying dexamethasone to mice induced catagen-like follicle changes significantly earlier and more consistently than a vehicle, such changes being useful for studying hair follicle regression.

This study introduces a mouse model of cyclophosphamide-induced alopecia, which effectively replicates human chemotherapy-induced hair loss and can be pharmacologically manipulated to study hair regrowth patterns.

In this study using the C3H/HeJ mouse model of alopecia areata, researchers found that hyperexpanded CD8⁺ T cell clones were sufficient to initiate disease, establishing a causal link between T cell clonality and pathogenicity.

This review discusses the roles of KIT and mast cells in skin physiology and pathology using different genetic models and reports no new clinical results; the authors suggest further exploration of KIT deficiency.