Rapid Thawing Enhances Tissue Destruction in a Mouse Model of Cutaneous Cryoablation: Insights into Oxidative Stress and Neutrophil Activation

    February 2025 in “ Journal of Dermatological Science ”
    Akiko Sekiguchi, Mai Ishikawa, Akihiko Uchiyama, Yoko Yokoyama, Sachiko Ogino, Ryoko Torii, Ryoko Akai, Takao Iwawaki, Sei‐ichiro Motegi
    Studysummary This study concluded that rapid thawing during cryoablation enhances neutrophil and lymphocyte infiltration, increases oxidative stress, and induces cell death, resulting in more substantial tissue damage in mice compared to natural thawing.
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