June 1996 in “Archives of Dermatology” Using a mix of finasteride and minoxidil can significantly regrow hair in men with pattern baldness.
1 citations
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January 2014 in “International Journal of Trichology” This case report describes a 35-year-old woman with diffuse partial woolly hair occurring alongside epidermolysis bullosa with mottled pigmentation.
58 citations
,
October 1993 in “International Journal of Dermatology” This study found that 2% topical minoxidil solution was significantly more effective than placebo in promoting new hair growth in women with androgenetic alopecia.
17 citations
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May 1998 in “Contact Dermatitis” Minoxidil can cause pustular allergic reactions on skin.
44 citations
,
October 1989 in “International Journal of Pharmaceutics” This study found that topical minoxidil solutions showed the highest skin permeation at 3-4% concentrations, with crystallization occurring at a 5% concentration due to vehicle component evaporation.
17 citations
,
March 1985 in “Journal of The American Academy of Dermatology” Minoxidil can lower blood pressure in some people.
18 citations
,
March 1985 in “Journal of The American Academy of Dermatology” Cocaine use can cause a blistering skin disease.
57 citations
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August 2003 in “British Journal of Dermatology” This study found that daily use of 1% pyrithione zinc shampoo modestly improved hair growth over 26 weeks, although these effects were less than those of 5% minoxidil.
80 citations
,
August 2002 in “Journal of Dermatology” This study found that combining oral finasteride with topical minoxidil resulted in the greatest improvement in hair growth for male patients with androgenetic alopecia, compared to using any single treatment.
38 citations
,
June 2005 in “Contact Dermatitis” This case report describes a patient with an allergic sensitization to minoxidil, indicating that such patients should pursue alternative therapies to treat androgenetic alopecia.
41 citations
,
March 1987 in “Journal of The American Academy of Dermatology” This study observed that 2% minoxidil solution was at least as effective as 3% for increasing hair growth and stabilizing bald areas in men with male pattern baldness.
53 citations
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March 1987 in “Journal of The American Academy of Dermatology” Minoxidil effectively regrows hair in male pattern baldness.
July 2024 in “Forum Dermatologicum” This review evaluates various topical treatments for androgenetic alopecia but does not provide new clinical findings, emphasizing the need for selecting therapies with limited systemic side effects.
16 citations
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March 2017 in “Journal of inclusion phenomena and macrocyclic chemistry” This study found that using 2-hydroxypropyl-ß-cyclodextrin (HP-ß-CD) to encapsulate minoxidil can create a stable aqueous solution, potentially replacing the need for organic solvents in topical treatments for androgenic alopecia.
198 citations
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October 2011 in “Journal der Deutschen Dermatologischen Gesellschaft” This article discusses the development of an evidence-based guideline for treating androgenetic alopecia and reports no new research results.
24 citations
,
March 1987 in “Journal of The American Academy of Dermatology” This study found that 1% and 2% topical minoxidil solutions resulted in clinically noticeable hair growth compared to lower doses or placebo in men with male pattern baldness.
11 citations
,
April 1990 in “Australasian Journal of Dermatology” This study found that 2% minoxidil solution significantly increased non-vellus hair counts and regrowth rates compared to placebo in men with early androgenic alopecia, suggesting it is an effective treatment.
127 citations
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July 1996 in “Journal of The American Academy of Dermatology” This study found that in women undergoing chemotherapy after breast surgery, topical minoxidil significantly shortened the duration of hair loss compared to a placebo without significant side effects.
128 citations
,
July 2009 in “International Journal of Pharmaceutics” This study found that penetration enhancer-containing vesicles significantly improved minoxidil delivery to the skin compared to traditional liposomes and penetration enhancer-containing ethanolic solutions, with deformability linked to enhanced deposition.
33 citations
,
October 2016 in “European Journal of Pharmaceutical Sciences” This study found that a novel effervescent formulation significantly increased minoxidil sulphate accumulation in hair follicles and skin compared to a standard minoxidil solution.
This study focused on developing a nanoemulsion-based gel for delivering minoxidil, aiming to enhance its contact time with the scalp and potentially improve skin absorption compared to conventional topical solutions.
May 2026 in “Revista Ensaios Pioneiros” This study developed and evaluated topical formulations containing 5% minoxidil and 1% rosemary essential oil for androgenetic alopecia treatment, finding them physically and chemically suitable, but noted that further stability tests and clinical trials are needed to confirm therapeutic efficacy and safety.
81 citations
,
March 2009 in “Seminars in Cutaneous Medicine and Surgery” This review discusses the classifications, diagnostic methods, and treatment strategies for female pattern hair loss, but reports no clinical results.
8 citations
,
May 1987 in “Journal of The American Academy of Dermatology” In this study, ultraviolet light did not significantly enhance or worsen hair growth induced by topical minoxidil in men with male pattern baldness.
67 citations
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March 1987 in “Journal of The American Academy of Dermatology” This study found that both 2% and 3% minoxidil resulted in a significant increase in hair counts for participants with androgenetic alopecia over 12 months.
4 citations
,
January 2009 in “Eclética Química” This study described a potentiometric titration method for determining minoxidil, which showed recoveries of 97.4 to 98.7% and agreed with chromatographic results within a 90% confidence level.
31 citations
,
October 2002 in “Dermatologic Surgery” This article reviews expert opinions on combining pharmacologic treatments like minoxidil with hair transplantation, reporting improved hair density and regrowth in patients with partially functioning follicles.
39 citations
,
April 2010 in “International Journal of Pharmaceutics” This study found that using monoolein cubic phase nanoparticles with an entrapped hydroxypropyl β-cyclodextrin/minoxidil complex increased minoxidil skin permeation, but minoxidil retention in the skin was higher with a traditional solution.
26 citations
,
June 2011 in “International Journal of Pharmaceutics” This study found that solid lipid nanoparticles with minoxidil were as effective as commercial solutions for skin penetration and were non-corrosive, indicating potential for hair loss treatment.
February 2024 in “Journal of Molecular Structure” In this study, researchers developed a supramolecular hydrogel combining minoxidil and salicylic acid, finding that it accelerates hair growth and enhances hair follicle regeneration in vivo, suggesting its potential as an effective treatment for alopecia.