research The Antiandrogen Enzalutamide Downregulates TMPRSS2 and Reduces Cellular Entry of SARS-CoV-2 in Human Lung Cells
The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.
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research Neuroimmunoregulation of Androgens in the Adrenal Gland and the Skin
Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.
research Cicatricial (Scarring) Alopecias: Comprehensive Review and Management
Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.
research Neuroendocrinology of Epithelial Hair Follicle Stem Cells
Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.
research Current and Potential Agents for the Treatment of Alopecia Areata
Current and future treatments for alopecia areata focus on immunosuppression, immunomodulation, and protecting hair follicles.
research Deciphering the Functions of the Hair Follicle Infundibulum in Skin Physiology and Disease
The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.
research Vasoactive Intestinal Peptide, Whose Receptor-Mediated Signaling May Be Defective in Alopecia Areata, Provides Protection from Hair Follicle Immune Privilege Collapse
A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.
research Effect of Long-Term Fluticasone Treatment on Immune Function in Horses with Heaves
Long-term fluticasone treatment does not harm the immune system in horses with heaves.
research Dermatoses of Pregnancy
Pregnancy can cause specific skin conditions that need correct diagnosis and treatment to protect both mother and baby.
research The Role of Vitamin D in Non-Scarring Alopecia
Low vitamin D might be linked to certain types of hair loss, and supplements could help, but more research is needed.
research FOXN1 Deficient Nude Severe Combined Immunodeficiency
FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.
research Study of Gene Expression Alteration in Male Androgenetic Alopecia: Evidence of Predominant Molecular Signaling Pathways
Hair loss involves immune responses, inflammation, and disrupted signaling pathways.
research Developing Stratified Epithelia: Lessons from the Epidermis and Thymus
The skin and thymus develop similarly to protect and support immunity.
research Cholesterol Homeostasis: Links to Hair Follicle Biology and Hair Disorders
Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.
research Genome-Wide Association Study of Skin Complex Diseases
Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.
research Thyroid Diseases and Skin Autoimmunity
Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.
research Immunology of Alopecia Areata
Alopecia areata, a type of hair loss, is likely an autoimmune disease with a genetic link, but its exact cause is still unknown.
research Group IID, IIE, IIF, and III Secreted Phospholipase A2s
Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
research Physical Methods for Topical Skin Drug Delivery: Concepts and Applications
New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.
research Sterol Intermediates of Cholesterol Biosynthesis Inhibit Hair Growth and Trigger an Innate Immune Response in Cicatricial Alopecia
Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.
research Interferons in Dermatology
Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.
research Multiple Sclerosis Disease-Modifying Therapies: Adverse Effect Surveillance and Management
The document concludes that managing side effects of MS therapies is crucial for treatment success and patient adherence.
research Identification of an Intronic Regulatory Element Necessary for Tissue-Specific Expression of Foxn1 in Thymic Epithelial Cells
A specific DNA region is crucial for Foxn1 gene expression in thymus cells but not in hair follicles.
research Effects of Mesenchymal Stem Cell Therapy on Alopecia Areata in Cellular and Hair Follicle Organ Culture Models
Mesenchymal stem cell therapy may help treat alopecia areata by promoting hair growth and reducing inflammation.
research The Changing Landscape of Alopecia Areata: The Translational Landscape
New treatments for hair loss are showing promise due to better understanding of genetics and the immune system.
research What's New in Cicatricial Alopecia?
New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.
research Hair Follicles and Their Role in Skin Health
Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.
research The Genetics of Alopecia Areata
Alopecia areata has a complex genetic basis that was not fully understood as of 2001.
research The Promise and Challenges of Cell Therapy for Psoriasis
Cell therapy shows promise for treating severe psoriasis but needs more research to confirm safety and effectiveness.
research Alopecia Areata: Clinical Perspective and an Insight into Pathogenesis
Alopecia areata causes hair loss due to an immune attack on hair follicles, influenced by genetics and environment.