June 2026 in “Drug Delivery and Translational Research” This study developed a spring-driven microneedle booster that improved early and cumulative delivery of minoxidil, accelerating hair regrowth compared to traditional roller methods in an androgenetic alopecia model.
February 2026 in “International Journal of Molecular Sciences” This study found that 3-hydroxypropionic acid improved the function of hair follicle cells under oxidative stress, suggesting potential as a treatment for stress-related hair loss.
3 citations
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July 2023 in “Biomolecules” This study reports that some human cell surface HLA-I molecules (including HLA-B27) can appear without their usual peptide component, potentially altering immune interactions, influencing arthritis development in specific mice models, and exhibiting upregulation in certain cancer cells.
1 citations
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June 2023 in “Chemical engineering journal” In this laboratory study, a novel minoxidil-loaded microneedle patch demonstrated potential for treating alopecia areata by promoting slow drug release and reducing application frequency, while exhibiting antibacterial properties to prevent infection during use.
February 2026 in “Clinical Cancer Research” This study found that combining the PAXMAN scalp cooling system with HairRepro MEDI α lotion led to a 50% success rate in reducing chemotherapy-induced alopecia and achieved complete hair regrowth by 3 months in Japanese breast cancer patients, suggesting enhanced efficacy over scalp cooling alone.
April 2024 in “Dermatologic surgery” This source does not report specific results or findings, instead it provides details about the affiliation of the researchers and reference details for the publication.
4 citations
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November 2020 in “Journal of the American Academy of Dermatology” This cohort study observed a bidirectional association between alopecia areata and migraine in Taiwanese patients, indicating that individuals with one condition have a higher risk of developing the other.
10 citations
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January 2003 in “Dermatology” This study describes a Japanese family with monilethrix and found no clear genotype/phenotype correlation in cases with the E413K mutation in hHb6.
April 2024 in “Skin research and technology” This study retrospectively observed that combining microneedle minoxidil with triamcinolone acetonide showed clinical efficacy in treating alopecia areata, a condition marked by sudden patchy hair loss.
April 2024 in “Journal of translational medicine” In this study, the researchers identified MJ04, a selective JAK3 inhibitor, as a promising candidate for promoting hair growth, demonstrating efficacy in both animal models and human hair follicle assays with a favorable safety and pharmacokinetic profile.
This study found that mycophenolate mofetil was well tolerated and effective as a second-line treatment for autoimmune hepatitis in patients who were intolerant to azathioprine.
10 citations
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September 1997 in “Molecular carcinogenesis” This study found that mirex and TPA promote papilloma formation in CD-1 mouse skin through distinct populations of mutant Ha-ras cells, resulting in additive tumor yields.
November 2017 in “Journal of cosmetology & trichology” The combined treatment of a specific hair cocktail and microneedling device effectively restores hair in different baldness patterns.
31 citations
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February 2007 in “Molecular Carcinogenesis” This study found that transgenic mice overexpressing human ATF3 showed hyperplastic and dysplastic changes in epithelial tissues, with a high incidence of oral cancer, suggesting potential oncogenic properties of ATF3.
50 citations
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November 2020 in “Physiology & behavior” This review found that patients with depression generally have higher hair cortisol concentrations compared to healthy controls, while those with PTSD tend to have lower concentrations.
2 citations
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May 2022 in “Advanced therapeutics” This study reported that a novel vasodilator drug called TOP-M119, when delivered using a specially designed dissolving microneedle system, showed enhanced targeting of hair follicles and effectiveness in treating alopecia, demonstrated through in vitro, ex vivo, and in vivo studies involving mouse skin.
July 2021 in “Indian journal of drugs in dermatology” In this study, the combination of intradermal meso-solution and topical 5% minoxidil significantly increased hair re-growth in men with androgenetic alopecia compared to minoxidil alone.
186 citations
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October 1957 in “A M A Archives of Dermatology” This paper presents a collection of unusual cases observed over seven years, with detailed histological descriptions but no definitive diagnoses, aiming to encourage further discussion and understanding of the disease process.
February 2023 in “Journal of Cosmetic Dermatology” This study found that microneedling combined with either topical vitamin D3 or bimatoprost was more effective for hair regrowth in localized alopecia areata than microneedling alone, though differences between the two additives disappeared after three months.
6 citations
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January 2016 in “Bioorganic & Medicinal Chemistry Letters” This study reported that certain minoxidil conjugates, specifically those with spermine, methylenedianiline, and diaminofluorene, were able to induce differentiation in HL-60 acute myeloid leukemia cells without toxicity at a concentration of 10 μM.
June 2026 in “Mendeley Data” This dataset provides supplemental material for a study on long-term particulate matter exposure and androgenetic alopecia risk, including additional exposure data and sensitivity analyses, but reports no new clinical results.
26 citations
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June 1988 in “PubMed” This study found that 3 percent topical minoxidil solution was ineffective in treating severe chronic alopecia areata, as it did not produce cosmetically acceptable hair regrowth.
September 2020 in “Benha Journal of Applied Sciences” In this study, researchers found that serum Myostatin levels and HOMA-IR were significantly higher in patients with androgenic alopecia compared to controls, suggesting they could be indicators of disease susceptibility and severity.
January 2025 in “ACS Materials Letters” This study developed a GelMA-based hydrogel system that supports all stages of severe burn wound healing by reducing inflammation and enhancing tissue regeneration, including neovascularization and hair follicle growth, potentially improving clinical outcomes for complex wounds with multidrug-resistant bacterial infections.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that OR-101, a selective JAK3/TEK inhibitor, was associated with dose-dependent improvements in hair growth in humanized mice with alopecia areata, suggesting its potential as a treatment option.
July 2026 in “Journal of King Saud University - Computer and Information Sciences” This study introduced a novel framework that significantly improves the accuracy of alopecia areata lesion segmentation in semi-supervised scenarios, outperforming existing methods and aiding in the disease's diagnosis, treatment, and staging, which can impact quality of life and mental well-being.
2 citations
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December 2022 in “Archives of Dermatological Research” In this study, researchers developed a new classification system for anterior hairline types among Asian males without androgenetic alopecia, finding MM, RM, and ML to be the most common types.
9 citations
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February 2019 in “BMC cancer” This study found that M30 may protect against cyclophosphamide-induced alopecia in mice by enhancing hair growth and preventing abnormal hair, suggesting its potential as a treatment.
This review discusses male androgenetic alopecia treatments, noting that topical minoxidil and oral finasteride are FDA-approved and require continuous use to maintain hair retention effects, but reports no new clinical results.
October 2025 in “Journal of Molecular Structure” Hyaluronic acid microneedles help deliver minoxidil derivatives effectively for hair regrowth.