TLDR The hydrogel system improves healing in infected burn wounds by reducing inflammation and promoting tissue repair.
The study presents a dual-response hydrogel system designed to enhance healing in infected burn wounds, particularly those complicated by multidrug-resistant bacteria. Traditional hydrogel dressings often target only one phase of the healing process, but this GelMA-based hydrogel system addresses both the inflammatory and proliferative stages. It effectively reduces hyperinflammatory infiltration and promotes neovascularization, hair follicle regeneration, and collagen deposition. This innovative approach offers a comprehensive solution for managing challenging wounds, aligning with clinical needs for improved healing outcomes.
10 citations,
April 2023 in “Acta biomaterialia” New hydrogel dressing with antibiotic speeds up burn healing and skin regeneration.
518 citations,
November 2014 in “Science” Skin grafting and wound treatment have improved, but we need more research to better understand wound healing and create more effective treatments.
11 citations,
July 2022 in “Journal of Materials Science: Materials in Medicine” A new hydrogel with stem cells from the human umbilical cord speeds up healing in diabetic wounds.
1 citations,
January 2024 in “Theranostics” Exosomes show promise for future tissue regeneration.
March 2025 in “Frontiers in Pharmacology” The hydrogel dressing rapidly heals wounds and promotes blood clotting better than existing options.
9 citations,
March 2023 in “Biomimetics” New materials that better mimic natural skin structure could improve healing, especially for chronic wounds.
January 2024 in “Regenerative Biomaterials” Metal organic frameworks-based scaffolds show promise for tissue repair due to their unique properties.
1 citations,
November 2023 in “Polymers” Polyurethane dressings show promise for wound healing but need improvements to adapt better to the healing process.
