Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that the film-trigger applicator system enhanced drug delivery efficiency and skin penetration of dissolving microneedles compared to traditional patch systems in both lab and animal models.

This study found that the 5α-reductase inhibitor finasteride affected phasic and tonic GABA A receptor-mediated currents differently in the thalamic reticular and ventrobasal nuclei of mice, suggesting endogenous neurosteroid modulation of these receptors.

This study found that clinicians frequently prefer cyclophosphamide over rituximab for induction therapy of childhood-onset systemic lupus erythematosus and ANCA-associated vasculitis, following a high-dose regimen recommended by the NIH.

In this study, 70% of female androgenetic alopecia patients who did not respond to standard minoxidil experienced clinical improvement after switching to a propylene glycol-free, witch hazel-based 5% minoxidil sulfate solution, with the treatment also being well-tolerated.

This article reviews current diagnosis and treatment approaches for diabetes in adolescents, emphasizing a team-based management strategy, but provides no new clinical findings.

In this study, socially defeated mice showed increased alcohol consumption, and CRF-R1 antagonism selectively reduced drinking in these mice, suggesting a potential treatment target for stress-related alcohol use disorders.

This study describes the effects of adrenocorticotropic hormone injections in rats, specifically detailing their stunted body growth and changes in visceral proportions and hematology.

This case study reports a 15-year-old Burmese girl with telogen effluvium after receiving incorrect medication due to a pharmacy auto-complete error.

Methylated gene parts may cause finasteride-resistance in some enlarged prostate patients.

The FDA approved using Cialis with Proscar for better treatment options.

This review details contemporary medical management options for benign prostatic hyperplasia, highlighting the expanding role of phosphodiesterase-5 inhibitors and beta-3 agonists, but reports no new clinical findings.

In this study, a mixture of tocopherol acetate, L-menthol, and stevioside was more effective in promoting hair growth in mice compared to tocopherol acetate or L-menthol alone.

This review provides a comprehensive overview of the mechanisms, efficacy, and adverse reactions of drugs commonly used for treating benign prostatic hyperplasia but reports no new clinical results.

This study found that microalgal extract from Botryococcus terribilis exhibited antidepressant-like effects in mice by regulating neuroinflammation and modulating neurotransmitter systems.

Finasteride blocks progesterone's effect on absence seizures in rats.

In this study, finasteride inhibited progesterone synthesis in mouse-derived MA-10 Leydig tumor cells by blocking cholesterol side-chain cleavage, but human and rat cells showed minimal sensitivity.

In this study, a new Finasteride conjugate showed stronger inhibition of 5α-reductase and similar reduction of prostate hyperplasia in rats compared to Finasteride, with potentially improved toxicity.

In this study, Zusanli acupoint injections of metoclopramide significantly improved dyspeptic symptoms in patients with functional dyspepsia more than oral domperidone, with no adverse reactions in either group.

In this case report, a 10-year-old girl with an adrenal adenoma experienced symptoms like hirsutism and clitoromegaly; after surgical removal of the tumor, her symptoms and biochemical abnormalities resolved over several months.

This research found that metformin promoted hair growth in vitro by activating the AMPK/β-catenin signaling pathway in dermal papilla and outer root sheath cells.

This study found that Finasteride Dispersible Tablets, prepared with an optimized prescription, disintegrate quickly, disperse well, and have a high dissolution speed, suitable for industrial production.

This study found that administering an alcoholic extract of Mentha spicata leaves significantly reduced testosterone levels and aggressive behavior in female rats with elevated testosterone, suggesting its potential protective role against such symptoms.

This case report describes an obese young adolescent girl with PCOS who presented with high testosterone levels and severe hyperinsulinemia, successfully treated with continuous combined oral contraceptives.

This study optimized a screening assay to identify molecules that inhibit or enhance TRPM5 ion channel activity, which may have implications for treating dysfunctions linked to cardiac arrhythmias and diabetes.

DHEA treatment helps grow pubic hair and boosts mood in girls with adrenal issues.

This study found that ethanol's ability to block long-term potentiation in rat hippocampal slices is influenced by neurosteroids that enhance GABA A receptor activity.

Nitrendipine and nifedipine effectively block muscle contractions, while papaverine relaxes them and minoxidil needs high amounts to work.

This study found that combining fructose and DHT in rats successfully mimicked the clinical phenotypes of non-lean PCOS, providing a novel rodent model for this condition.

This study found that the activity of CD73, an enzyme expressed in the hair follicle epithelium, may regulate human hair growth by modulating adenosine production.

Taking 5 mg/day finasteride can cause side effects in women with hair loss, but these are usually mild and fade over time, making the treatment beneficial in the long run.