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This study suggests that finasteride use is not significantly associated with a reduced risk of advanced hepatic fibrosis or inflammation in HCV-positive males, with ethnically-divergent findings for methadone requiring further investigation.

This study found that a specific amino-pyridine compound showed potent androgen receptor antagonist activity, stimulating hair growth in mice and reducing sebum production in a hamster model.

This article reviews methotrexate's pharmacokinetics and toxicity, emphasizing the role of urinary excretion and leucovorin in avoiding most toxic reactions; it provides no new clinical results.

This study reported that derivatization with 5-butylpicolinic acid improved the sensitivity for detecting testosterone and DHT in saliva using LC-ESI-MS/MS, with minimal interference from the saliva matrix.

This study found that midazolam improved PTSD-associated behavioral deficits in rats through its action on the TSPO, CBR, and neurosteroidogenesis pathways.

In this animal study, agmatine exhibited a protective effect against seizures related to hormone fluctuations, with results suggesting that its anticonvulsant properties may involve interactions with central neurosteroids in female rats experiencing progesterone withdrawal.

This study found that monitoring endogenous steroid metabolites in serum may improve the detection of testosterone doping by highlighting promising biomarkers.

This study demonstrates that a single exposure to GHB during a sexual assault can be detected by analyzing hair segments collected about one month after the incident.

This study concluded that 16β-methyl-17α-benzoyloxypregnen-4-en-3,20-dione may be a promising treatment for androgen-dependent diseases and epilepsy due to its antioxidant effects and impact on GABAergic and serotonergic metabolism in rats.

This study found that thalamic GABAA receptor α4 subunit levels increased after prolonged ethanol exposure and were regulated by phosphorylation and neuroactive steroids following acute high-dose ethanol administration.

This article describes standard methods for studying DNA methylation dynamics in mouse skin and hair follicle stem cells but presents no new research findings.

In this study, finasteride-treated WAG/Rij rats showed a significant increase in spike-wave discharges when administered endogenous steroids THPROG and THDOC, indicating potential exacerbation of absence seizures.

In this animal study, the methanolic extract of Crataeva nurvala leaves was found to possess sedative and anxiolytic properties, potentially linked to GABAergic activity and certain neuroactive compounds.

In this study on tolerant rats, maternal and developmental toxicity from levo-alpha-acetyhnethadol hydrochloride were observed at all doses, without specific fetal toxicity or teratogenic effects.

In this study, topical application of α-methylspermidine during the telogen phase in mice induced hair growth by increasing the polyamine pool and mimicking the anagen phase's characteristics.

This study found that methionine supplementation improved hair follicle density in heat-stressed Rex rabbits, likely through various signaling pathways, despite an increase in stress indicators.

The researchers reported that the rat Hershberger assay reliably detected endocrine-disrupting effects of finasteride, procymidone, and 17α-methyltestosterone, validating the assay's sensitivity for identifying hormonal activity.

This study discusses how chronic ethanol exposure and withdrawal affect GABAA receptor subunit expression and function, finding that some changes can be selectively blocked by certain drugs like diazepam and finasteride.

This study evaluated a menthol-based microemulsion for transdermal delivery of finasteride and silodosin, finding that it enhanced skin permeation and flux compared to aqueous solutions, suggesting a promising method for managing benign prostatic hyperplasia.

This study highlights the public health significance of androgenic-anabolic steroid use disorder, emphasizing health risks, societal effects, and the need for routine AAS analyses in forensic autopsies, especially in athlete deaths.

The researchers reported a case of falsely elevated testosterone in a teen, due to immunoassay interference, demonstrating that liquid chromatography tandem-mass spectrometry provides more accurate testosterone measurement, emphasizing the need for thorough analysis when clinical results are inconsistent.

This study found that microalgal extract from Botryococcus terribilis exhibited antidepressant-like effects in mice by regulating neuroinflammation and modulating neurotransmitter systems.

This study investigated the metabolic pathways of epristeride, a new Type II 5α‐reductase inhibitor, using in vitro models and found that its metabolites show significant interactions with key proteins, suggesting implications for its role in doping control.

This case study reported that a 40-year-old woman with Graves' disease developed severe thrombocytopenia after starting methimazole, suggesting a rare but serious risk of methimazole-induced immune thrombocytopenia and underscoring the need for close monitoring.

This study suggests that finasteride may inhibit the enzyme phenylethanolamine N-methyltransferase, which could contribute to its sexual and psychological side effects.

In this study, thalamic GABAA receptor α4 subunit levels were regulated after acute and chronic ethanol exposure, with temporal expression changes affected by phosphorylation state and neuroactive steroids.

This study developed dissolving microneedles using specific polymers for transdermal delivery of rizatriptan benzoate, demonstrating improved drug skin penetration and significant alleviation of migraine symptoms in vivo compared to passive diffusion, suggesting potential advantages over conventional treatment methods for acute migraine.

In this study, oral Tribulus terrestris extract significantly increased MSH expression in mouse hair follicle melanocytes, suggesting enhanced melanocyte activity and migration.