24 citations
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January 2015 in “International Journal of Trichology” This research observed that among young men with androgenic alopecia, there was a significant association with metabolic syndrome compared to healthy controls, suggesting AGA as a potential early marker for metabolic risk.
22 citations
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January 2019 in “Hormone and Metabolic Research” This meta-analysis confirmed associations between some androgenic and metabolic parameters in women with PCOS, suggesting that these measurements might help predict metabolic risk in this population.
2 citations
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September 2023 in “Health science reports” This meta-analysis found a strong association between metabolic syndrome and certain skin diseases, including psoriasis, hidradenitis suppurativa, androgenetic alopecia, and lichen planus, suggesting increased risk compared to the general population.
June 2026 in “International Journal of Dermatology Venereology and Leprosy Sciences” This study found that while alopecia areata was not significantly associated with metabolic syndrome, patients showed higher blood pressure and fasting blood sugar levels, suggesting a potential increased risk of future metabolic disorders.
December 2022 in “Sri Lanka Journal of Diabetes Endocrinology and Metabolism” This study found a significant association between early onset androgenetic alopecia and metabolic syndrome, with higher prevalence of metabolic risk factors in affected individuals compared to a control group.
1 citations
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January 2017 in “International Journal of Research in Medical Sciences” This study found that metabolic syndrome was 4.6 times more common in patients with androgenetic alopecia than in controls, particularly among those with severe grades, suggesting a higher risk of cardiovascular diseases.
28 citations
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July 2015 in “American Journal of Clinical Dermatology” This study found a higher prevalence of metabolic syndrome in patients with lichen planus, especially those with mucosal involvement, which is associated with increased cardiovascular and diabetes risk.
1 citations
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May 2023 in “Annales d'Endocrinologie” In this study, researchers found that metformin improved glycaemic control and other metabolic parameters in non-diabetic patients on glucocorticoid treatment, also reducing pneumonia risk and hospital admissions, suggesting a potential advantage for routine use in this population.
1 citations
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August 2009 in “ACTUALIDAD MEDICA” In this study, early-onset androgenetic alopecia patients showed a higher prevalence of metabolic syndrome and carotid atheromatosis compared to a control group, suggesting the need for cardiovascular risk screening in this population.
November 2024 in “IP Indian Journal of Clinical and Experimental Dermatology” This study discusses the multifactorial causes of metabolic syndrome and its association with various skin conditions, indicating an increased risk of diabetes and cardiovascular issues, emphasizing the need for early lifestyle interventions and medical management.
January 2024 in “The Egyptian Journal of Hospital Medicine ” This study highlights a potential link between androgenetic alopecia and metabolic syndrome, suggesting that understanding this association could enhance strategies for screening and managing cardiovascular risk in affected individuals.
This study found a direct correlation between IL6 and insulin, glucose, and cholesterol serum levels in patients with oral lichen planus, suggesting a potential increased cardiovascular risk.
January 2017 in “IP Indian journal of clinical and experimental dermatology” This study found that metabolic syndrome was significantly more common in men with early-onset androgenetic alopecia compared to controls, indicating a potential increased risk of cardiovascular issues in this population.
December 2021 in “Biomarkers” This study found that men with early-onset male pattern alopecia did not significantly differ from healthy individuals in cardiovascular and metabolic measures, but hsCRP and galectin-3 were linked to cardiovascular risk factors in those with the condition.
91 citations
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July 2022 in “Frontiers in Endocrinology” This study reported that Chinese women with PCOS exhibited diverse lipid profiles based on different characteristics, which may help understand their increased risk of cardiovascular disease.
May 2026 in “RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218” This study reviewed recent scientific evidence on the neuroendocrine and metabolic impacts of chronic use of 5-alpha reductase inhibitors, detailing its association with sexual dysfunction, mood disorders, insulin resistance, and other metabolic disorders, suggesting persistent biopsycho-social risks beyond transient side effects in users.
March 2025 in “Forum Dermatologicum” This review explores links between metabolic syndrome and skin diseases, reporting shared mechanisms like inflammation and hormonal imbalances that may influence conditions such as acne, rosacea, psoriasis, and alopecia, and emphasizes the importance of managing cardiovascular risks in affected patients.
June 2024 in “Ecotoxicology and Environmental Safety” This study observed that chronic and acute exposure to finasteride negatively impacted development, reproduction, and gene expression in Daphnia magna, highlighting the environmental risks of this pharmaceutical for freshwater ecosystems.
November 2025 in “Frontiers in Immunology” In this study, researchers found significant links between specific metabolic reprogramming-related genes and alopecia areata risk, highlighting increased SQSTM1 expression in affected hair follicles compared to healthy ones.
January 2026 in “Nutrición Hospitalaria” In this study, researchers identified significant signals indicating previously unrecognized risks of lipid metabolism abnormalities for several drugs, urging the need for better monitoring and label updates.
28 citations
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February 2023 in “Healthcare” This study found a notably high prevalence of metabolic syndrome among apparently healthy individuals in Pakistan, with high triglycerides, low HDL, and central obesity identified as significant risk factors.
17 citations
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January 2014 in “Journal of Clinical and Diagnostic Research” This study found that patients with oral lichen planus and oral lichenoid reactions have higher levels of serum cholesterol and LDL-C than healthy individuals, suggesting a potential elevated risk for cardiovascular disease.
7 citations
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January 2016 in “Clinical Hemorheology and Microcirculation” In this study, patients with androgenetic alopecia showed no difference in insulin resistance or prevalence of metabolic syndrome but had higher cardiovascular risk due to increased inflammatory markers and lipoprotein(a) levels.
January 2024 in “Indian Journal of Dermatology” This study found that women with FPHL may have an increased cardiovascular risk, as indicated by associations with metabolic syndrome, insulin resistance, and elevated biochemical markers.
3 citations
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September 2025 in “Frontiers in Cardiovascular Medicine” This study reports that women with polycystic ovary syndrome, especially those with a hyperandrogenic pattern, are at a higher risk for cardiovascular disease compared to other PCOS patients, likely due to related metabolic comorbidities.
13 citations
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March 2019 in “Physiological Research” This study found that among women with polycystic ovary syndrome, higher levels of the hormones estrone and free testosterone were associated with an increased cardiometabolic risk, especially in those who were overweight or obese.
May 2025 in “Nutrition and Diabetes” This study found that elevated 1-hour plasma glucose in women with PCOS was associated with increased risk of metabolic disorders and gestational diabetes, indicating it may be a useful marker for adverse metabolic status.
November 2025 in “Fertility Gynecology and Andrology” This study highlights that polycystic ovary syndrome develops through genetic and environmental factors, with insulin resistance as a key mechanism, impacting the risk of metabolic and cardiovascular conditions.
December 2025 in “Frontiers in Endocrinology” This study found that elevated CgA levels in PCOS are associated with obesity, insulin resistance, and low-grade inflammation, suggesting CgA may be a novel biomarker for metabolic risk stratification in PCOS.
April 2024 in “Russian Journal of Preventive Medicine” This review discusses how skin changes like acanthosis nigricans and psoriasis can indicate metabolic syndrome components such as insulin resistance and dyslipidemia, suggesting a potential role for early diagnosis and treatment in reducing cardiovascular risks associated with the syndrome.