research Health Benefits Attributed to 17α-Estradiol, a Lifespan-Extending Compound, Are Mediated Through Estrogen Receptor α
17α-estradiol extends lifespan and improves metabolism in male mice through the estrogen receptor α.
Search
for
Sort by
Research
30-60 / 1000+ results 
research Transdermal Permeation of Drugs in Various Animal Species
Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.
research Lifestyle Intervention and Anti-Obesity Therapies in Polycystic Ovary Syndrome: Impact on Metabolism and Fertility
Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.
research Ovarian Morphology Is Associated With Insulin Resistance In Women With Polycystic Ovary Syndrome: A Cross-Sectional Study
Larger ovarian size is linked to higher insulin resistance in women with PCOS.
research Reconsidering PCOS Etiology, Diagnosis, Clinical Subgroups, and Subgroup-Specific Treatments
Different types of PCOS need specific diagnosis methods and treatments.
research The Effects of High-Intensity Interval Training on Vaspin, Adiponectin, and Leptin Levels in Women with Polycystic Ovary Syndrome
High-intensity interval training improves certain hormone levels and lipid profiles in women with PCOS.
research Impact of Metformin and Rosiglitazone Treatment on Glucose Transporter 4 mRNA Expression in Women with Polycystic Ovary Syndrome
Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.
research The Effect of Weight Loss and Treatment with Metformin on Serum Vaspin Levels in Women with Polycystic Ovary Syndrome
Weight loss and metformin don't significantly change vaspin levels in women with PCOS.
research Vitamin D Receptor Polymorphisms and Polycystic Ovary Syndrome: A Systematic Review
The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.
research Respiratory Regulation by Steroids in Newborn Rats: A Sex-Specific Balance Between Allopregnanolone and Progesterone Receptors
Breathing in newborn rats is affected differently by hormones based on their sex.
research Cardiovascular Risk Associated With Gender Affirming Hormone Therapy in Transgender Population
Hormone therapy increases the risk of heart-related issues in transgender women and may affect heart health in transgender men.
research Prostate Specific Antigen in Diagnosis of Polycystic Ovarian Syndrome: A New Insight
PSA levels are higher in women with PCOS, but FAI is a more accurate marker for diagnosis.
research The Comparative Effects Between Long-Term and Short-Term Treatment of Finasteride on Anxiety-Like and Depression-Like Behaviors in Early Senescent Male Rats
Long-term Finasteride treatment reduces depression better than short-term treatment in rats.
research Hyperandrogenemia in Women with Polycystic Ovary Syndrome: Prevalence, Characteristics, and Association with Body Mass Index
High levels of male hormones are very common in women with PCOS and affect their metabolism differently depending on their weight.
research Metabolic Syndrome and the Skin: A More Than Superficial Association
Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.
research Afamin Serum Concentrations Are Associated With Insulin Resistance and Metabolic Syndrome in Polycystic Ovary Syndrome
High afamin levels are linked to metabolic syndrome and may predict its development in women with insulin resistance.
research Prevalence of Dermatologic Manifestations and Metabolic Biomarkers in Women with Polycystic Ovary Syndrome in North China
Women with PCOS in North China often have hirsutism and acne, with hirsutism linked to metabolic issues.
research Comparison of Components of Metabolic Syndrome in Androgenic Alopecia Versus Healthy Population
People with androgenic alopecia are more likely to have metabolic syndrome than healthy individuals.
research Polycystic Ovary Syndrome: A Complex Condition with Psychological, Reproductive, and Metabolic Manifestations That Impacts Health Across the Lifespan
Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.
research Metabolic Features of the Reproductive Phenotypes of Polycystic Ovary Syndrome
Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.
research Phenotype and Metabolic Profile of South Asian Women with Polycystic Ovary Syndrome: Results from a Specialist Endocrine Clinic
South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.
research The Prevalence of Metabolic Disorders in Various Phenotypes of Polycystic Ovary Syndrome: A Community-Based Study in Southwest Iran
Different types of PCOS have different levels of metabolic problems, with the most severe type showing the highest disturbances.
research Metabolic Syndrome and Metabolic Risk Profile According to Polycystic Ovary Syndrome Phenotype
Women with severe types of PCOS are more likely to have metabolic syndrome, and belly fat is a key predictor of this risk.
research Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men
Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
research The Role of Non-Aromatizable Testosterone Metabolite in Metabolic Pathways
Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.
research Characterization of Metabolic Changes in the Phenotypes of Women with Polycystic Ovary Syndrome in a Large Mediterranean Population from Sicily
Women with PCOS in Sicily show different levels of metabolic problems depending on their PCOS type, with obesity and abnormal lipid profiles being common.
research Age-Related Differences in the Reproductive and Metabolic Implications of Polycystic Ovarian Syndrome: Findings in an Obese, United States Population
Older obese women with PCOS have higher cardiovascular and metabolic risks despite lower androgen levels.
research Gynecologic and Andrologic Dermatology and the Metabolic Syndrome
Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.
research Raising Threshold for Diagnosis of Polycystic Ovary Syndrome Excludes Population of Patients with Metabolic Risk
Changing the diagnosis criteria for PCOS might miss women at risk for related health issues.
research Metabolic Dysfunction in Female Mice with Disruption of 5α-Reductase 1
Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.