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The document concludes that hirsutism can be managed with various treatments tailored to the individual, potentially improving quality of life.

Brazilian women with PCOS and both menstrual irregularity and high male hormone levels have a higher chance of having metabolic syndrome.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

Oestrogens are key for bone growth during puberty in both boys and girls.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Older obese women with PCOS have higher cardiovascular and metabolic risks despite lower androgen levels.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

Ingesting Leucaena leucocephala caused hair loss and increased infant mortality in ringtailed lemurs.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Finasteride safely lowers DHT levels without affecting testosterone.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

Finasteride side effects in young men may be linked to specific gene variations.

Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.

Vacuum massage may improve skin elasticity and induce changes in skin cells, but evidence for treating burn scars is insufficient and more research is needed.

Hirsutism is a strong sign of high male hormones and metabolic problems in women with PCOS, but acne and hair loss are not.

Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

Finasteride and dutasteride may cause metabolic issues like liver disease and diabetes.

Early-onset baldness is linked to genetics, lifestyle, and can indicate higher risk for heart and metabolic diseases, and affects mental health.

Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.

The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.

People with androgenetic alopecia (hair loss) may have a higher risk of developing metabolic syndrome.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.

Trilostane may help delay epilepsy development by increasing certain brain chemicals.

Abusing steroids can damage your heart, muscles, reproductive system, liver, skin, and brain, and may increase the risk of Alzheimer's disease.

Spironolactone can cause side effects like high potassium levels and breast enlargement, and patients need careful monitoring.

Myo-inositol helps improve skin conditions and metabolic profiles in young women with PCOS.

Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.

PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.