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Netherton syndrome can cause severe dehydration, infections, and growth issues in infants.

Hyperandrogenism increases heart disease risk in premenopausal women, but this risk is linked to obesity in postmenopausal women.

A woman lost over 80% of her hair due to a condition called telogen effluvium after having COVID-19.

Polycystic Ovary Syndrome (PCOS) can lead to diabetes, heart disease, cancer, and mental health problems.

High testosterone increases heart disease risk in women with PCOS.

The document concludes that careful history and physical exams are crucial for accurately diagnosing polycystic ovary syndrome and distinguishing it from other similar conditions.

Oxidative stress plays a significant role in vitiligo, and both skin and non-skin cells may be involved.

Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.

PCOS is a long-term condition that needs more research for better understanding and treatment.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Phytotherapeutic compounds and supplements can help manage Polycystic Ovarian Syndrome (PCOS).

Lower LDL-c levels predict higher COVID-19 mortality.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

Finasteride in male rats causes liver and metabolic issues in their offspring.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Testosterone reduces heart damage and inflammation after injury.

The document concludes that managing PCOS requires a comprehensive approach, including lifestyle changes and medication, to improve symptoms and reduce health risks.

PCOS may increase the risk of certain cancers.

Acne patients have higher levels of mTOR in their skin, which could be linked to future metabolic disease.

Excess androgens may cause PCOS, not just be a symptom.

Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

Women with PCOS have lower ghrelin levels and a weaker response to sugar, which might affect their feeling of fullness and lead to overeating.