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Oxidative stress plays a significant role in vitiligo, and both skin and non-skin cells may be involved.

Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.

Long-term finasteride treatment reduces depression and brain issues in obese male rats.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

PCOS is a common hormonal disorder in women, marked by symptoms like hair growth and menstrual issues, and requires personalized treatment.

Vitamin D is important for bones, hair, blood pressure, and breast development.

Lower LDL-c levels predict higher COVID-19 mortality.

Understanding glycans and enzymes that alter them is key to controlling hair growth.

Early-onset AGA shows different hair and metabolic characteristics compared to normal-onset AGA.

Different types of PCOS need specific diagnosis methods and treatments.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Psoriasis involves immune and genetic factors, and understanding these can improve treatments.

Women with PCOS have higher hair cortisol levels, which are linked to worse metabolic and inflammatory conditions.

CBG may help with various medical conditions but needs more human research to confirm safety and effectiveness.

Phytotherapeutic compounds and supplements can help manage Polycystic Ovarian Syndrome (PCOS).

PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Myotonic Dystrophy may age cells faster, and drugs that target aging could be potential treatments.

Manipulating cell cleanup processes could help treat hair loss.

PCOS is a long-term condition that needs more research for better understanding and treatment.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

High fasting insulin levels in women with PCOS are linked to a higher risk of heart and metabolic problems.

PCOS in lean women is a serious health condition with implications beyond fertility, affecting metabolism and increasing cardiovascular disease risk.

Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.

Genetic variations greatly affect individual metabolism and can impact health and disease risk.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Metformin effectively improves metabolic symptoms in women with PCOS, while alfacalcidiol does not have a significant impact.

Selenium might help with insulin resistance and cholesterol in PCOS, but more research is needed to confirm its benefits.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.