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PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Sebocytes play a key role in controlling androgen levels in human skin.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

JAK inhibitors help with skin conditions but need more research on dosing and safety.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.

Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.

Hair color loss can indicate the effectiveness of a drug targeting the KIT protein in mice and humans.

Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

Topical JAK inhibitors may help treat some skin conditions but need more research.

JAK inhibitors help regrow hair in alopecia areata patients, improving their quality of life.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Tamoxifen effectively treats gynecomastia without causing impotence.

Endocrine therapies for cancer significantly increase the risk of hair loss.

Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.

The research suggests that the global distribution of PCOS is likely due to historical human migration and that genes affecting PCOS may have different impacts on males and females.

Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.

High levels of androgens during early development may cause PCOS-like symptoms.

Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.

Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.

LED light therapy may help hair growth by activating certain cell pathways.

Most pregnant women experience skin darkening and hair changes, with these effects usually going away after giving birth.

Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.

Melatonin may help treat PCOS symptoms in rats.

Some drugs can cause hair loss, excessive growth, or color changes, often reversible but sometimes permanent.

Dermoscopy has improved skin cancer diagnosis and has expanding applications in dermatology, but requires staying updated with new research and techniques.

Genetic data can predict male-pattern baldness with moderate accuracy, especially for early-onset cases in some European men.

Oestrogen and thyrotropin-releasing hormone affect prolactin and its receptor in human skin and hair, suggesting new treatment options for related conditions.

Women with PCOS tend to have higher anxiety and depression levels compared to healthy women.