Tamoxifen for Flutamide/Finasteride-Induced Gynecomastia

December 1997 in “ Urology ”

Victoria R. Staiman, Franklin C. Lowe

tamoxifen flutamide finasteride gynecomastia prostate carcinoma Nolvadex Eulexin Propecia

Studysummary This study found that low-dose tamoxifen may effectively treat painful gynecomastia in patients receiving flutamide and finasteride for advanced prostate cancer. Our plain-language summary of this paper — not a Tressless recommendation.

Tamoxifen is an effective treatment for gynecomastia caused by flutamide/finasteride combination therapy in patients with advanced prostate carcinoma. Studies have shown that low-dose tamoxifen can reduce breast size and tenderness without causing impotence. Tamoxifen is a viable alternative to surgery for the treatment of gynecomastia.

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Research cited in this study

2 / 2 results

research The Effect of Finasteride in Men with Benign Prostatic Hyperplasia

1040 citations , October 1992 in “The New England Journal of Medicine”

In this study, 5 mg of finasteride per day significantly improved urinary symptoms and reduced prostate volume in men with benign prostatic hyperplasia, but increased the risk of sexual dysfunction.

research New Methods of Endocrine Management of Prostatic Cancer

67 citations , January 1987 in “The Journal of urology/The journal of urology”

New hormonal therapies can help treat advanced prostate cancer but may cause testicular issues.