155 citations,
August 2003 in “Journal Of Experimental Zoology Part B: Molecular And Developmental Evolution” Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.
153 citations,
November 2004 in “Current Medicinal Chemistry” The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.
152 citations,
October 2010 in “Archives of Dermatology” Finasteride helps hair growth but may cause sexual side effects.
152 citations,
January 2004 in “Current anthropology” Humans lost body hair relatively recently in evolution.
150 citations,
February 2013 in “Surgical Infections” Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.
150 citations,
October 2012 in “Clinical Endocrinology” Women with PCOS have a higher risk of diabetes and heart problems, especially when they get older.
150 citations,
February 2008 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Antiandrogens are somewhat effective in reducing excessive hair growth in women.
149 citations,
December 2007 in “The Journal of Clinical Endocrinology and Metabolism” Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.
147 citations,
January 2014 in “American Journal of Clinical Dermatology” Laser device increases hair density, safe for treating hair loss in men and women.
147 citations,
June 2011 in “New England journal of medicine/The New England journal of medicine” 5α-reductase inhibitors may prevent prostate cancer but could also raise the risk of more severe cancers.
145 citations,
November 2017 in “Journal of The European Academy of Dermatology and Venereology” Use minoxidil for hair loss treatment; assess results after 6 months.
144 citations,
August 2019 in “Cells” The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
141 citations,
August 2018 in “Nature Reviews Microbiology” Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.
141 citations,
August 2017 in “Developmental Dynamics” The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.
140 citations,
February 2020 in “Frontiers in Plant Science” RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.
139 citations,
October 1999 in “Environmental Health Perspectives” Modern science supports the use of some Ayurvedic plants for health, as ancient practices suggested.
138 citations,
May 2000 in “Maturitas” Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.
136 citations,
April 2013 in “Clinical Cancer Research” The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.
136 citations,
January 2013 in “International Journal of Trichology” 134 citations,
January 2010 in “Biomedical research” Low oxygen conditions increase the hair-growing effects of substances from fat-derived stem cells by boosting growth factor release.
134 citations,
June 2005 in “Neuropsychopharmacology” GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.
132 citations,
July 2000 in “Lupus” In Italian patients with lupus, the most common skin issue was chronic cutaneous lupus, especially discoid lesions, and nonspecific skin problems occurred in about a third of those with systemic lupus, mainly during active disease.
131 citations,
September 2010 in “The Laryngoscope” Forehead modification greatly increases the perception of femininity and is a safe procedure.
130 citations,
February 2018 in “Journal of Investigative Dermatology” Tofacitinib may help treat severe hair loss, but more research is needed.
129 citations,
January 2019 in “Clinical medicine insights” Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.
128 citations,
February 2016 in “British Journal of Dermatology” Alopecia areata significantly lowers the quality of life, especially in emotional and mental health aspects.
127 citations,
May 2004 in “PubMed” Finasteride may help some male chronic pelvic pain patients, but more research needed.
126 citations,
February 2017 in “JAMA Surgery” Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.
126 citations,
January 2009 in “International Journal of Trichology” Oxidative stress contributes to hair graying and loss as we age.
124 citations,
March 2012 in “JAMA” Testosterone's muscle-building effects do not require its conversion to DHT.