243 citations,
October 2003 in “Developmental biology” Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.
85 citations,
July 2012 in “Cold Spring Harbor perspectives in biology” The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
64 citations,
January 2010 in “The FASEB Journal” Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.
62 citations,
October 2010 in “Journal of biomedical nanotechnology” Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.
21 citations,
March 2018 in “Experimental Dermatology” The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.
4 citations,
August 2017 in “Journal of cutaneous pathology” An 8-year-old girl had a rare, benign skin tumor on her forehead.
117 citations,
May 2017 in “Human Reproduction Update” The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.
38 citations,
January 2014 in “International Journal of Endocrinology” Adrenal disorders can cause lasting brain and behavior issues in children.
26 citations,
April 2019 in “Genes” lncRNA XLOC_008679 and gene KRT35 affect cashmere fineness in goats.
25 citations,
August 2017 in “Animal Biotechnology” Researchers found that certain RNA molecules might play a role in the growth of Cashmere goat hair.
8 citations,
January 1996 in “Springer eBooks” Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.
4 citations,
October 2012 in “Expert Review of Dermatology” Dermoscopy greatly improves melanoma diagnosis and reduces unneeded surgeries.
2 citations,
December 2023 in “Royal Society of Chemistry eBooks” Hair is a complex organ, and understanding its detailed structure and growth phases is crucial for analyzing substances within it.
January 2023 in “Biomaterials Science” Certain genes are more active during wound healing in axolotl and Acomys, which could help develop materials that improve human wound healing and regeneration.
47 citations,
August 2016 in “American Journal Of Pathology” Fibroblast changes in systemic sclerosis may help understand disease severity and treatment.
235 citations,
July 1999 in “Journal of biological chemistry/The Journal of biological chemistry” Human hair is made up of different keratins, some strong and some weak, with specific types appearing at various stages of hair growth.
26 citations,
February 2016 in “Respiratory Medicine” Auto-antibody testing is a useful but not definitive tool in diagnosing interstitial lung diseases, and using a specific algorithm could make testing more cost-effective.
14 citations,
May 2017 in “InTech eBooks” Hair is important for protection, social interaction, and temperature control, and is made of a growth cycle-influenced follicle and a complex shaft.
9 citations,
June 2023 in “Cells” Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
1 citations,
April 2023 in “Animals” Deleting the EDAR gene in Cashmere goats affects genes and proteins related to hair growth.
2 citations,
January 2019 in “Medizinische Genetik” The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.
88 citations,
January 2019 in “Journal of Tissue Engineering and Regenerative Medicine” Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.
170 citations,
November 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin can heal wounds without hair follicle stem cells, but it takes a bit longer.
34 citations,
February 2015 in “Frontiers in Cellular Neuroscience” Zebrafish helped find new ways to prevent drug-induced hair cell death and potential treatments for hearing loss.
82 citations,
February 2017 in “Cold Spring Harbor Perspectives in Biology” The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
47 citations,
May 2020 in “Cardiovascular Research” The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.
118 citations,
October 2013 in “Trends in Genetics” The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.
6 citations,
October 2022 in “Frontiers in Cell and Developmental Biology” Transplanted hair follicle stem cells can heal damaged rat intestines.
53 citations,
May 1987 in “The Lancet” The document suggests a possible link between Crohn's disease and Johne's disease and calls for more research.
26 citations,
October 2017 in “Scientific reports” A special microbe helps plants absorb rock phosphate by growing on their root hairs.