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This review discusses the advancements and challenges in developing in vitro human skin models incorporating components like vasculature for drug testing and disease research, but reports no new clinical results.

This review explores the diverse roles and heterogeneity of fibroblasts across different organs, highlighting their potential involvement in both normal tissue functioning and fibrotic diseases, but reports no new experimental results.

This review discusses emerging treatments and mechanisms for alopecia, highlighting potential therapies like janus kinase inhibitors and advances in stem-cell technology, but reports no new experimental results.

In this study, researchers developed a wearable red and blue LED patch and a sprayable fibrin gel to treat infected wounds at home, demonstrating effective infection control and enhanced wound healing in diabetic mice and minipigs.

This study presents case reports of four patients with alopecia areata or alopecia universalis, highlighting varied responses to treatments like prednisone, intralesional triamcinolone, and squaric acid dibutyl ester.

This study found that melatonin exposure promoted hair follicle fiber growth in Cashmere goat cultures, potentially influencing pathways related to the microvascular system and extracellular matrix.

This study found that conditional knockout of N-WASP in keratinocytes of mice led to skin barrier defects, increased immune cell infiltration, and hyperproliferation of keratinocytes, indicating its crucial role in skin homeostasis.

This study identified 77 genes with significant expression changes in expanded human skin, suggesting possible mechanisms for skin regeneration during tissue expansion, including previously unreported genes like HOXA5, HOXB2, and AP1.

In this study, researchers demonstrated that human hair keratins can self-assemble into stable nanofibrous networks in vitro, which are compatible with human skin cells and useful for regenerative applications.

This study demonstrated that Gelfoam® histoculture supports extensive growth of both hair shafts and sensory nerves from isolated mouse whisker follicles over prolonged periods.

This study found that ingenol mebutate treatment led to gene expression changes in actinic keratoses, with complete lesion clearance in 40% of patients and identified genetic markers potentially predicting treatment response.

In this study, researchers using single nuclei RNA-sequencing found that fibroblasts in deeper layers of mouse skin expressed higher levels of pro-inflammatory genes post-wounding compared to other cells, highlighting their significant role in early inflammation and tissue repair processes.

In this study, mice on a methionine-deficient diet experienced hair loss, which was not remedied by homocysteine supplementation; hair regrowth only resumed after methionine was reintroduced, suggesting dietary methionine is essential for hair maintenance.

This study discusses the epithelial-immune microenvironment in chronic skin diseases, such as psoriasis and atopic dermatitis, and highlights current and future treatment strategies targeting inflammatory loops within these diseases.

This study found that RANKL signaling enhances CD8+ T cell-mediated anti-viral immunity during herpes simplex virus infection by preventing apoptosis of Langerhans cells, suggesting potential therapeutic applications.

This chapter discusses the concepts of regeneration and homeostasis, noting that in vertebrates, regeneration is limited to certain tissues like liver, blood, and bone.

In this study, researchers found that Hdac1 and Hdac2 are crucial for maintaining the quiescence and survival of dermal papilla cells in the hair follicle, regulating the hair cycle by controlling cell-cycle genes and Wnt signaling.

This review examines advancements in deep learning methods for detecting dermatological conditions from dermoscopic images, summarizing available datasets and suggesting future research directions, but reports no new results.

This study found that Ift20 is essential for hair follicle stem cell identity and hair regrowth, and it regulates keratinocyte migration during wound healing through focal adhesion integrin recycling, independently of ciliogenesis.

This source discusses how radiotherapy-induced skin fibrosis, a chronic side effect affecting cancer survivors' quality of life, is driven by ongoing inflammation and fibroblast activity, and emphasizes the need for comprehensive dermatologic management and better diagnostic tools.

This narrative literature review examined how linking embryonic development with non-genetic skin anomalies can improve diagnostic accuracy, guide prenatal counseling, and enrich dermatology education by revealing specific vulnerabilities in skin morphogenesis and supporting advances in regenerative medicine.

The study introduced an advanced skin model, ImmuSkin-MT, which effectively distinguished between different strengths of skin sensitizers by mimicking the interaction of immune cells in skin tissue.

This review discusses the use of single-cell RNA sequencing and spatial transcriptomics to enhance understanding of the pathogenesis and targeted therapies for chronic inflammatory skin conditions, highlighting technology advancements and the need for cost reduction and standardization.

This study found that aqueous extract of Pueraria mirifica, when administered to a rat model, significantly reduced prostate weight, prostatic index, and serum dihydrotestosterone levels, while also improving prostate histomorphology, suggesting its potential as an anti-BPH treatment.

This study identifies key transcriptomic features and a necessary dermal niche for eccrine gland development, advancing potential regenerative approaches for these vital skin appendages.

This study demonstrated that cryogelation of human hair keratin allows the development of 3D scaffolds with tunable properties, supporting cell adhesion and proliferation for potential biomedical applications.

This study reported the expression patterns and potential functions of long non-coding RNAs in the hair follicle cycle of yak, with insights into their sequence conservation between yak and cashmere goat.

Eating a balanced diet with specific nutrients can help manage menopause symptoms and prevent related health issues.

This chapter reviews the skin's structure and its clinical relevance, highlighting connective tissue diseases and the potential for novel treatments like protein, cell, or stem cell transfer, but reports no new findings.

This study found that treatment with PTH-CBD stimulated hair growth in mice with alopecia areata, with increased levels of beta catenin indicating activation of the Wnt pathway.