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D'orenone stops root hair growth by disrupting auxin transport, but adding auxin can reverse this.

Agouti protein affects melanocortin receptors through competitive antagonism and receptor down-regulation.

3,4,5-tri-O-caffeoylquinic acid promotes hair growth by activating the β-catenin pathway.

Two drugs, ritlecitinib and brepocitinib, improved scalp hair loss condition markers.

Melanocyte stem cells are crucial for skin pigmentation and have potential in disease modeling and regenerative medicine.

Stopping mitochondrial respiration can prevent brain cancer spread in skin cancer patients, and plant compound β-sitosterol could help achieve this.

CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.

Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

New treatments like nanotechnology show promise in improving skin cancer therapy.

Certain daily habits like stress, diet, and sleep can affect the severity of hair loss in alopecia areata.

The skin is a large organ that plays a role in the immune system.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.

δ-GABAA receptors affect alcohol consumption based on the estrous cycle and influence movement regardless of the cycle.

The workshop discussed the role of a protein called calreticulin in health and disease, its potential as a treatment target, and its possible use as a disease marker.

Gut microbes significantly affect brain steroid levels.

Innate immunity genes in hair follicle stem cells might have new roles beyond traditional immune functions.

Scientists made structures that look like human hair follicles using stem cells, which could help grow hair without using actual human tissue.

Pili torti is a rare condition where hair is twisted and breaks easily, often linked to genetic disorders or other health issues.

Taking triterpenoids from Ganoderma lucidum over a long time can help slow down brain aging and improve overall health in mice.

Defects in certain proteins cause major heart abnormalities during early development.

Autophagy helps keep skin healthy and may improve treatments for skin diseases.

Engineered vesicles from macrophages help hair growth in mice and humans.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

A special receptor in sensory nerve endings helps control how they respond to stretching.

Exosomes could be effective for improving skin health and treating skin diseases.

Mast cells and CD8 T cells interact closely in skin diseases, affecting each other's behavior and contributing to conditions like psoriasis and eczema.