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Intralesional chemotherapy with 5-fluorouracil and methotrexate may worsen keratoacanthoma-type skin cancer in transplant patients.

The document concludes that the skin is a complex organ providing protection, sensation, and healing, with challenges in treating conditions like itchiness.

Stem cell research and regenerative medicine have made significant advancements in treating various diseases and conditions.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

FOL-005, a hair growth promoter, acts locally on mouse skin where injected and could be a promising hair loss treatment.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

Auxin and ethylene hormones both work together and against each other to control plant growth.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Estrogen therapy can reduce skin aging but has cancer risks.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.

Genetics and hormones cause hair loss; finasteride treats it safely.

Minoxidil needs activation to work, and minoxidil sulfate helps with hair growth and blood pressure.

Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Botulinum toxin has potential for treating various skin conditions and improving wound healing.

Mutations in the PTPRQ gene cause significant balance issues in mice due to hair bundle defects in the inner ear.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.

Targeting CD200 could be a new treatment for rheumatoid arthritis.

Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.

Exercise improves insulin sensitivity and hormone regulation in PCOS rats.

Activin activation in skin cells speeds up wound healing without affecting scar quality.

Astaxanthin is a safe antioxidant that may improve heart, skin, eye health, and physical performance, and help manage chronic diseases.