January 2024 in “Uttar Pradesh journal of zoology” In this study, researchers found that chemical treatments like bleaching can cause severe damage to the hair cuticle, with previously modified hair showing complete deterioration compared to the partial degradation seen in virgin hair, highlighting the need for mindful cosmetic practices.
163 citations
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April 2019 in “Nature Communications” This study found that mechanical skin stretching can stimulate hair stem cell proliferation and hair regeneration by activating a complex pathway involving WNT, BMP-2, and M2 macrophages.
103 citations
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January 2006 in “Journal of Cell Science” This review summarizes the major events and regulators of the hair cycle in mammals but reports no new experimental results; it emphasizes the complex regulation of stem cell activation and differentiation during hair growth.
48 citations
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February 2013 in “Molecular and Cellular Endocrinology” This review discusses the presence of the StAR protein in 17 non-classical steroidogenic tissues, suggesting that advanced detection methods are needed for a complete understanding of its functions in these tissues.
34 citations
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August 2002 in “British Journal of Dermatology” This study observed that two patients treated with interferon α-2b and ribavirin for chronic hepatitis C experienced complete and reversible straightening of their natural curly hair, which recurred with treatment resumption.
24 citations
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October 2014 in “Cold Spring Harbor Perspectives in Medicine” Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
17 citations
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August 2024 in “Discover Nano” This review summarizes that polyesters hold promise for vascular tissue engineering due to their mechanical properties and biodegradability, but optimizing their use in repairing damaged blood vessels remains challenging due to the complexity of vascular tissues.
14 citations
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October 2020 in “Natural Products and Bioprospecting” This review discusses current topical treatments, natural products, and complementary therapies for androgenetic alopecia, but it reports no new clinical results.
8 citations
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May 2019 in “Journal of dermatological treatment” This study found that vismodegib was effective in treating basal cell carcinoma, achieving complete remission in some patients; however, significant side effects often required careful management to prevent therapy suspension, which can lead to resistance.
3 citations
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December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study revealed key cellular dynamics and interactions during early embryonic mouse skin development, highlighting complex transitions from precursor states to diverse multilayered structures.
June 2026 in “International Journal of Bioprinting” This review found that 3D bioprinting significantly advances skin tissue engineering by enabling the creation of complex, patient-specific skin structures, though technological and regulatory challenges persist, particularly in areas like scalability and physiological mimicry.
January 2026 in “Immune Network” This review discusses the heterogeneity of Tregs in normal and tumor environments, emphasizing the complexity of targeting tumor-resident Tregs while maintaining systemic immune tolerance, but reports no new findings.
August 2025 in “Bioscientia Medicina Journal of Biomedicine and Translational Research” In this case study, a 3-year-old with tinea capitis achieved complete resolution following treatment, highlighting hair salons as potential indirect transmission sites for infection and emphasizing trichoscopy's diagnostic value when traditional signs like Wood’s lamp fluorescence are missing.
August 2025 in “Frontiers in Immunology” This case report is the first to document the coexistence of bullous pemphigoid, malignant tumors, and alopecia areata in a patient, highlighting the complete resolution of skin lesions with dupilumab and spontaneous hair regrowth without disease-specific treatment.
January 2024 in “Advances in Dermatology and Allergology” This review explores the inflammatory pathogenesis and clinical presentation of hidradenitis suppurativa, highlighting the complexity of treatment and the impact on patients' quality of life, while also examining emerging therapeutic options.
September 2021 in “Meditsinskiy sovet = Medical Council” This study found that injecting blood plasma enriched with platelet growth factors significantly improved the healing and auditory function in patients with acute post-traumatic tympanic membrane perforation compared to natural regeneration.
This study found that lateral root formation in plants in response to L. bicolor volatiles involves complex signaling processes, potentially including unknown proteins, CRKs, and ABA pathways.
This section presents 70 multiple choice questions designed for haematology specialist trainees, covering complex clinical cases and their likely diagnoses, adverse events, and management advice.
43 citations
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June 2018 in “Clinics in dermatology” This review discusses the variety of skin disorders associated with atopic dermatitis, exploring their complex relationships and shared genetic and environmental factors, but reports no new clinical results.
3 citations
,
January 2011 in “Female pelvic medicine & reconstructive surgery” This review discusses the impact of hormones on female sexual function and dysfunction, highlighting the complexity and gaps in basic research, and reports no new clinical findings.
1 citations
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March 2014 in “TURKDERM” This review discusses the life cycle and homeostasis of hair follicles, highlighting their development and the complex signaling between dermal and epithelial cells, but it reports no new clinical results.
March 2026 in “International Journal of Dermatology Venereology and Leprosy Sciences” This study describes vitiligo as an autoimmune disease marked by depigmented skin and mucosal patches, and reviews its complex pathogenesis and diagnostic features. Treatment aims for disease control and repigmentation through various topical and systemic therapies, phototherapy, and surgical options, emphasizing personalized, multimodal approaches.
February 2026 in “Clinical Cosmetic and Investigational Dermatology” This study highlights how combining genetic and environmental risk assessments could advance early screening and personalized prevention for vitiligo, given its genetic complexity and environmental interactions.
December 2023 in “Indian Journal of Canine Practice” In this case report, a 3-year-old beagle with recurrent skin lesions and alopecia due to a methicillin-resistant Staphylococcus aureus infection showed significant improvement within 10 days and complete resolution after a 28-day treatment with oral linezolid, alongside fungal infection management.
46 citations
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April 1977 in “Southern Medical Journal” In this study, five women with minoxidil-induced hypertrichosis achieved complete hair removal using a calcium thioglycolate depilatory agent, with minimal or no skin irritation.
1308 citations
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March 1998 in “Journal of bone and mineral research” This review discusses the molecular role of the vitamin D receptor in regulating various biological actions such as bone mineralization and reports no new clinical results, highlighting the complexity of vitamin D's function in multiple tissues.
34 citations
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May 2021 in “Journal of Nanobiotechnology” This study found that electrospun short fibrous sponges effectively mimic the 3D extracellular matrix, promoting tissue regeneration, angiogenesis, and wound healing in diabetic rats better than 2D fiber membranes.
31 citations
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September 2016 in “PLoS ONE” The researchers reported that in hairless mice, epidermal cell division orientations and epidermal thickness varied by body site, with dorsal and ear epidermis primarily dividing parallel to the basement membrane, unlike hind paw and tail epidermis.
13 citations
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October 2010 in “Pharmacogenomics” This study constructed a panel of pharmacokinetic and pharmacodynamic genes, revealing that current SNP chips insufficiently capture many drug-response gene variants, highlighting the need for complementary genetic approaches.
6 citations
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September 2021 in “Experimental Brain Research” In this study, researchers found that the glabrous skin of the rat forelimb contains sparse Meissner corpuscles and Merkel complexes, with more slowly adapting afferents in the palm and rapidly adapting afferents in the digit extremity.