Hidradenitis Suppurativa: A New Therapeutic Approach For An Old Disease

January 2024 in “ Advances in Dermatology and Allergology ”

Marta Billewicz, Joanna Wojtania, Anna Woźniacka

hidradenitis suppurativa chronic inflammatory disease hair follicles inflammation

Studysummary This review explores the inflammatory pathogenesis and clinical presentation of hidradenitis suppurativa, highlighting the complexity of treatment and the impact on patients' quality of life, while also examining emerging therapeutic options. Our plain-language summary of this paper — not a Tressless recommendation.

Hidradenitis suppurativa (HS) is a chronic inflammatory disease marked by painful nodules and abscesses, primarily due to inflammation within hair follicles. This condition often recurs, complicating treatment and negatively affecting patients' psychological well-being and quality of life. The article reviews the pathogenesis and clinical presentation of HS, with a focus on exploring new therapeutic options to manage this challenging disease.

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research The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside

144 citations , November 2020 in “Frontiers in immunology”

This study summarizes how the IL-23/IL-17 axis contributes to inflammatory skin diseases like psoriasis and highlights that biologics targeting this pathway, including monoclonal antibodies against IL-23 and IL-17, have shown efficacy in clinical trials for these conditions.

research Finasteride for the Treatment of Hidradenitis Suppurativa in Children and Adolescents

62 citations , March 2013 in “JAMA Dermatology”

This case series reported that three pediatric patients with hidradenitis suppurativa showed decreased frequency and severity of disease flares after treatment with oral finasteride, with no significant adverse effects.