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    Glossary Melanoma Cells

    cancerous cells originating in pigment-producing melanocytes

    Melanoma cells are cancerous cells that originate in melanocytes, the cells responsible for producing melanin, the pigment that gives skin its color. These cells can grow uncontrollably and spread to other parts of the body, making melanoma one of the most dangerous forms of skin cancer. Early detection and treatment are crucial for improving survival rates.

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    1. The Comparison of In Vitro Photosensitizing Efficacy of Curcumin-Loaded Liposomes Following Photodynamic Therapy on Melanoma MUG-Mel2, Squamous Cell Carcinoma SCC-25, and Normal Keratinocyte HaCaT Cells Pharmaceuticals · 2021 · 48 citations
    2. [4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs Biochemical Pharmacology · 2007 · 26 citations
    3. Carvone Decreases Melanin Content by Inhibiting Melanoma Cell Proliferation via the Cyclic Adenosine Monophosphate (cAMP) Pathway Molecules · 2020 · 12 citations
    4. Finasteride inhibits melanogenesis through regulation of the adenylate cyclase in melanocytes and melanoma cells Archives of Pharmacal Research · 2018 · 11 citations
    5. Assessment the Effect of Ficus carica Leaf Extract on B16F10 Melanoma Cancer Cells: The Roles of p53, Caspase-3 & Caspase-9 on Induction of Intrinsic Apoptosis Cascade Jundishapur Journal of Natural Pharmaceutical Products · 2021 · 1 citations
    6. 1272 p21Waf1/Cip1 is differentially expressed in epidermal versus follicular melanocytes and melanoma cells and is phenotypically regulated by UVB-mediated apoptosis 2023
    7. Stimulation of melanogenesis by Carthamus tinctorius floret extract in B16F10 murine melanoma cells วารสารเภสัชศาสตร์อีสาน (Isan Journal of Pharmaceutical Sciences, IJPS) · 2013
    8. Dual aspects of B cells in tumor immunity; B cells are capable of positive and negative regulation for tumor immunity against B16 melanoma Journal of Dermatological Science · 2017
    9. Human melanocyte development and melanoma dedifferentiation at single cell resolution bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 9 citations
    10. A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease Nature Communications · 2019 · 67 citations
    11. Epidermal and Hair Follicle Progenitor Cells Express Melanoma-Associated Chondroitin Sulfate Proteoglycan Core Protein Journal of Investigative Dermatology · 2004 · 51 citations
    12. 644 Tumor cell adhesion as a risk factor for SLN metastasis and predictor of disease recurrence in primary cutaneous melanoma Journal of Investigative Dermatology · 2016
    13. Melanoma: Genetic Abnormalities, Tumor Progression, Clonal Evolution and Tumor Initiating Cells Medical Sciences · 2017 · 37 citations
    14. Nestin is expressed in HMB‐45 negative melanoma cells in dermal parts of nodular melanoma The Journal of Dermatology · 2010 · 9 citations
    15. 1379 Cell of origin contributes to the melanoma diversity Journal of Investigative Dermatology · 2018
    16. ‘Malignant melanoma microecosystem’: Immunohistopathological insights into the stromal cell phenotype Experimental and Therapeutic Medicine · 2011 · 8 citations
    17. Ethanol extract of asiasari radix preferentially induces apoptosis in G361 human melanoma cells by differential regulation of p53 BMC Complementary and Alternative Medicine · 2019 · 2 citations
    18. Dormant tumor cells in ret transgenic mouse melanoma model and their interaction with memory T cells heiDOK (Heidelberg University) · 2012
    19. 0959 Effects of M1 homeopathic complex on human melanoma cells Journal of Investigative Dermatology · 2025
    20. Effect of adipose-derived stem cell-conditioned medium on the proliferation and migration of B16 melanoma cells Oncology Letters · 2015 · 23 citations
    21. Fibroblast heterogeneity and functions: insights from single-cell sequencing in wound healing, breast cancer, ovarian cancer and melanoma Frontiers in genetics · 2024
    22. Activation of TRPV4 Induces Exocytosis and Ferroptosis in Human Melanoma Cells International Journal of Molecular Sciences · 2022 · 24 citations
    23. Differential effects of dehydroepiandrosterone (DHEA) between mouse and human melanoma cell lines 2016
    24. Morphologic comparison of cultured human epidermis melanocytes,amelanotic melanocytes from hair follicles and mouse melanoma cells observed by atomic force microscope Linchuang pifuke zazhi · 2003
    25. A case of bullous pemphigoid in a malignant melanoma patient following an increased Th2/Th1 ratio in peripheral blood cells after nivolumab treatment European Journal of Dermatology · 2023 · 1 citations
    26. <i>In-Vitro</i> Effect of Sex Steroids on Mouse Melanoma (B16F10) Cell Growth CellBio · 2014 · 11 citations
    27. Regulated Proenkephalin Expression in Human Skin and Cultured Skin Cells 2010 · 77 citations
    28. Regulation of melanocyte stem cell behavior by the niche microenvironment Pigment Cell & Melanoma Research · 2018 · 24 citations
    29. N-(3,5-Dimethylphenyl)-3-Methoxybenzamide (A3B5) Targets TRP-2 and Inhibits Melanogenesis and Melanoma Growth 2011 · 15 citations
    30. An exclusive review of melatonin effects on mammalian melanocytes and melanoma Experimental dermatology · 2022 · 3 citations