11 citations
,
December 2016 in “Frontiers in Psychology” In this study, researchers used computer-generated models to demonstrate that subtle changes in hair diameter, density, and style significantly affect perceptions of age, health, and attractiveness.
73 citations
,
January 2013 in “Annals of Dermatology” This study observed that patients with various types of hair loss had significantly lower serum zinc levels compared to healthy controls, suggesting zinc disturbance may play a role in the condition.
December 2022 in “Himi, himijn tehnologijn hùrèèlèngijn èrdèm šinžilgèènij bùtèèl” This study found that using the "Khalgai" hair care products enriched with copper and zinc for 28 days led to increased hair density, diameter, and follicular unit count in women, indicating improved hair morphology.
July 2018 in “International journal of clinical & experimental dermatology” This narrative review describes the components of human hair and their nutritional importance but reports no clinical results; the authors suggest dietary sulfur amino acids are essential for hair health.
June 2026 in “Quality in Sport” This narrative review analyzed the literature on premature hair graying, identifying potential contributors such as nutrient deficiencies, oxidative and emotional stress, smoking, genetic factors, autoimmune diseases, and medication side effects, but reported no effective treatment to reverse it, underscoring the necessity for further research.
21 citations
,
January 2014 in “Dermatology Research and Practice” This study found no significant difference in serum and hair levels of iron, zinc, and copper between female alopecia areata patients and healthy controls.
1 citations
,
January 2016 in “American Journal of Clinical and Experimental Medicine” This study found that men with androgenic alopecia had significantly different hair copper levels compared to controls, but no difference in blood copper levels between the groups was observed.
7 citations
,
January 2017 in “Journal of cosmetology & trichology” This article discusses how nutritional and environmental factors, along with antioxidant supplementation, may improve hair growth by mitigating the effects of androgens and reports no new clinical results.
3 citations
,
May 2014 in “InTech eBooks” This review discusses the genetic and androgen-related factors in androgenetic alopecia, highlighting a specific polymorphism in the AR protein associated with male pattern hair loss, and reports no new clinical results.
1 citations
,
December 2022 in “Middle East Journal of Science” This review covers hair dye formulations, their mechanisms, and potential applications, but reports no new findings; the authors highlight the process of oxidative dyeing and repairing damaged hair.
November 2025 in “Biological Trace Element Research” This pilot study found no significant relationship between blood and hair mineral concentrations in generally healthy adults, though hair analysis may have potential for assessing long-term mineral trends.
January 2017 in “International journal of clinical & experimental dermatology” This review discusses how nutritional and lifestyle modifications, including antioxidant use, may enhance hair growth and prevent hair loss without the need for Finasteride, but provides no new clinical findings.
16 citations
,
October 2015 in “Photochemistry and photobiology” This study found that higher concentrations of copper (II) ions in human hair increase protein oxidative modification, contributing to hair damage regardless of UV exposure and pigmentation level.
14 citations
,
April 2000 in “Animal Science/Animal science” This article explores how various nutrients and metabolic processes impact wool and hair follicle function in animals but reports no new experimental findings.
11 citations
,
September 2012 in “Chinese science bulletin/Chinese Science Bulletin” This study found that variations in mineral content of hair, such as increased Zr in asthma and respiratory infections, may be linked to different illnesses, suggesting potential diagnostic use.
8 citations
,
January 2019 in “Chirurgia” In this study, adolescent patients undergoing laparoscopic bariatric surgery at a specialized center experienced significant reductions in BMI over 36 months, with no major perioperative complications, highlighting the procedure's safety and effectiveness for treating adolescent obesity in experienced settings.
11 citations
,
February 2018 in “Amino acids” This study found that homocysteine-keratin accumulation in human hair increases towards the tips, linked to copper/iron-catalyzed demethylation of methionine, and may contribute to keratin damage.
June 2018 in “Korean Journal of Family Practice”
10 citations
,
May 1986 in “Experientia” This animal study found that second generation mice exposed to excess zinc during gestation and lactation had reduced plasma copper, body weight, and hematocrit, with lighter and delayed hair development compared to mice on a normal zinc diet.
5 citations
,
January 1976 in “Acta Dermato Venereologica” This study found that sodium and potassium hair levels may serve as sex-specific indicators, with slight differences in copper and iron content between males and females, particularly during the female reproductive period.
1 citations
,
November 2023 in “Frontiers in veterinary science” Goat hair shows changes in metal levels and stress when goats move from indoors to mountain pastures.
3 citations
,
June 2022 in “Cells” This study reports improved methods for harvesting and processing keratinocytes from plucked human hair, enhancing their utility in generating donor-specific induced pluripotent stem cells more efficiently and reliably.
73 citations
,
May 1976 in “JAMA” This case report associates severe zinc deficiency with long-term total parenteral nutrition, suggesting the need for trace element supplementation in such nutritional management.
4 citations
,
May 2022 in “Journal of Drug Delivery Science and Technology” This research observed that nanoliposomes delivering a combination of bioactive peptides significantly promoted hair growth in vitro and in vivo by enhancing the proliferation and function of hair growth-targeted cells in C57BL/6 mice, suggesting a promising approach for treating androgenetic alopecia.
1 citations
,
December 2022 in “Bioactive Materials” In this study, researchers developed a nanocomposite microneedle patch containing copper/zinc dual-doped silica nanoparticles, which release substances to promote hair follicle regeneration by targeting various pathophysiological aspects of androgenic alopecia, presenting an effective anti-hair loss treatment strategy.
26 citations
,
July 2021 in “Frontiers in Cell and Developmental Biology” This review discusses mesenchymal stromal cell-conditioned medium for various skin conditions and found improvements in wound healing, hair restoration, and more, but emphasizes the need for further research to validate these findings.
51 citations
,
March 1986 in “Acta Dermato Venereologica” This study found no differences in trace element concentrations between Finnish alopecia patients and the normal population, but noted significant serum copper variation among different alopecia subtypes.
45 citations
,
March 2020 in “ACS Applied Materials & Interfaces” In this study, researchers created a novel fibrous membrane inspired by ancient Chinese medicine that effectively promotes hair follicle regeneration and wound healing in deep burn injuries by releasing quercetin, copper, and silicon ions.
This review discusses the association between hair element levels and autism spectrum disorder, reporting links between neurotoxic elements like mercury and lead and pathogenesis, alongside potentially protective roles for zinc and copper balance.
3 citations
,
January 2005 in “Biological & Pharmaceutical Bulletin” This study reports that the peptide GPIGS, found in Bacillus sp. M18 conditioned medium, may promote hair growth through the PI-3K/Akt pathway and accelerate hair regrowth in mice.