Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study on mice found that activating TRPML channels with MLSA1 promoted hair regeneration, accelerated hair cycle transition, and influenced human dermal papilla cells to secrete hair growth promoting factors while reducing hair growth inhibitors and oxidative damage.

This study suggests that a novel micropatterned dermal–epidermal matrix (μDERM) enhances keratinocyte function and epidermal morphology, offering potential improvements in skin substitute design for wound healing applications.

This study found that adalimumab treatment led to regression of lesions in two patients with hidradenitis suppurativa after 16 weeks of therapy.

This study found that teledermatology significantly reduced wait times and increased appointment availability for uninsured Latino immigrants, effectively triaging 70% of cases without in-person visits.

This study found that combining microdermabrasion, a topical regimen, and low-fluence QS Nd:YAG laser treatment effectively cleared melasma in women, with 81% of participants achieving over 75% clearance and minimal side effects.

This study found that DHEA significantly inhibited growth and induced autophagy in a mouse melanoma cell line, but showed only muffled inhibition and induced apoptosis in a human melanoma cell line.

In this case report, the authors found that pigmented demodicosis, caused by Demodex mites, led to facial hyperpigmentation in a 16-year-old male and showed significant improvement with oral isotretinoin and topical ivermectin treatment.

This case study reports that a police dog's pododemodicosis lesions resolved completely six months after a treatment regimen of ivermectin, antibacterial drugs, and beta-glucan.

This study presents a new method called scMC that effectively distinguishes biological from technical variation in single-cell genomics datasets, demonstrating its ability to accurately align and detect biological signals across various experiments.

This study observed that DNA damage response (DDR) plays a key role in pressure overload-induced cardiomyocyte hypertrophy, with disruption of the ATM kinase pathway potentially modulating this hypertrophy in mice.

In this report, a 19-year-old Japanese man experienced severe and prolonged urticarial reactions following treatment with diphenylcyclopropenone for alopecia universalis, emphasizing the need for caution with potent sensitizers.

In this study, DOP treatment improved hair regrowth in androgenetic alopecia by altering local steroid metabolism and follicular morphology.

This study developed a molecular systems architecture to map the complex interactions between mesenchymal stromal cells and their microenvironment, providing a framework for future predictive models that could enhance therapeutic strategies and reduce adverse effects.

This discussion reviews the shift in pharmaceutical strategy towards evidence-based and structure-guided drug development, highlighting ongoing challenges and efforts in computer-aided drug design without presenting new clinical results.

This study developed a new HPLC method for detecting prohibited substances like minoxidil and hydrocortisone in cosmetic products, achieving high sensitivity and successful application to real-world samples.

This study found that certain C57BL/6 mouse substrains have a genetic vulnerability to skin lesions resembling central centrifugal cicatrical alopecia in humans, potentially worsened by high vitamin A levels.

This case report describes a 4-year-old girl with hypotrichosis and juvenile macular dystrophy, linked to mutations in the cadherin 3 gene affecting P-cadherin expression.

In this study, researchers found that dermoscopy revealed specific features in Malassezia folliculitis, such as folliculocentricity and perilesional erythema, which can aid in its identification and potentially distinguish it from acne vulgaris.

This study found that Prdm1 is crucial for whisker development in mice, affecting multiple signaling pathways and possibly playing a role in primates' evolutionary loss of vibrissae.

This study found that the Elecsys AMH Plus immunoassay with a cutoff of 3.2 ng/mL is effective for diagnosing polycystic ovarian morphology, showing high sensitivity and specificity across different PCOS phenotypes.

This study describes a novel method using force-triggered density gradient sedimentation for efficiently isolating dermal papilla cells from neonatal mouse skin, showing promise for hair follicle regeneration research.

This case report details a middle-aged man with multiple sclerosis who developed difficult-to-evaluate skin reactions after daclizumab treatment, noting only slight improvement with additional therapies.

This case study indicates that older patients with NMOSD may show favorable clinical improvements with aggressive treatment, even when the intervention is initiated later in the disease course.

This study discusses the development of deep learning models for diagnosing skin disorders and notes challenges such as lack of data for darker skin tones, without providing new clinical results.

This study proposed a simple, rapid permanganometric method for determining minoxidil concentrations in pharmaceutical samples, offering comparable accuracy to chromatographic methods with recovery rates of 94.5 to 95.2%.

In this study, the researchers analyzed skin samples from Dun Mongolian horses to uncover molecular pathways linked to the "Bider" marking, identifying differential gene expression and several pigment-related signaling pathways that may play key roles in its formation.

This case report describes the first use of laser capture microdissection to confirm that atypical lymphocytes in a folliculotropic mycosis fungoides case involving the central nervous system were part of the same tumor clone.

This study found that increased MSI2 expression in hair follicle stem cells can delay hair growth by maintaining stem cell quiescence and repressing Hedgehog signaling.

This report describes a rare case of folliculotropic and syringotropic CD8 mycosis fungoides with unusual widespread mucosal involvement.

This study found that multiphoton microscopy effectively visualizes the microstructure of in vivo mouse skin, offering a clear view of various skin layers and components like corneocytes and collagen fibers.