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Changes in hair follicle structure may help diagnose and monitor alopecia.

This study highlights the distinct distribution patterns of extracellular matrix components in the scalp skin of male and female androgenetic alopecia patients, with increased elastin staining intensity observed in male cases.

This study by Bansaccal et al. found that skin with higher levels of type I collagen density and elasticity in the dermis can inhibit basal cell carcinoma development and spread by acting as a natural barrier against cell reprogramming in mice.

Reactive lipids from aging cells change the extracellular matrix, affecting cell function and inflammation.

In this study, researchers found that an injectable solution of low-molecular-weight hyaluronic acid and amino acids significantly improved skin rejuvenation and elasticity in the labia majora of post-menopausal women over 12 weeks, with a reported 25% or greater aesthetic improvement and high patient satisfaction.

This study found that in human hair bulbs, telomerase is present mainly in the nuclei of cells undergoing proliferation, particularly in the matrix epithelium during the anagen phase, and sparsely in the outer root sheath during late catagen and telogen phases.

This study examined the formation of acquired curved hair and found that the fusion of hair matrix cells during follicle regeneration contributes to asymmetric follicle shapes and curved hair, potentially linked to changes in type IV collagen and protein expression levels.

Homemade hair treatments can significantly lower drug levels in hair, possibly causing false-negative drug tests.

This study explored the molecular communication between hair matrix cells and dermal papilla cells in cashmere goats, revealing key ligand-receptor pairs and signaling pathways that facilitate intercellular crosstalk and potentially influence hair growth mechanisms.

This study found significant differences in mRNA and miRNA expression between yak dermal papilla cells and epidermal hair matrix cells, suggesting important roles for these molecules in hair follicle development.

This study found that carefully engineered hydrogels and asymmetric morphogen gradients facilitated the formation of anatomically relevant skin organoids from iPSC-derived EBs, improving pigmentation and hair follicle generation.

This study found that genetic ablation of Tet genes in mice led to changes in hair structure and keratin gene expression, indicating a role for Tet-mediated 5hmC DNA oxidation in hair follicle development and cycling.

This study introduces the term "hair matrix cyst" for a cyst with both pilomatricoma and epidermal cyst characteristics, highlighting its potential for misdiagnosis among similar skin conditions.

This study found that DPP4 is significantly involved in matrix deposition and fibrosis in human skin fibroblasts, although the exact functions of DPP4 remain unclear.

This study suggests that mechanical tension significantly impacts lymphocyte function, and that a complete lymphocyte population is essential for effective wound healing and reducing inflammation.

This paper presents a new methodology combining magnetic tweezers and traction force microscopy to study keratinocyte mechanobiology, but reports no experimental results yet.

This study identified several age-related changes in gene expression associated with the extracellular matrix of scalp dermal fibroblasts, which may impact hair follicle maintenance in women over 40.

This study observed that ECMs produced by papillary fibroblasts showed the largest fibers and supported keratinocyte differentiation better than reticular fibroblast matrices, informing biomimetic material design for skin tissue engineering.

This study suggests that β-Catenin and extracellular matrix components interact in a regulatory loop to influence fibroblast behavior and wound repair properties in dermal tissue.

Different substances affect hair and skin cell growth in various ways.

This review suggests that allogenic adipose stem cell and extracellular matrix transplants may be safe and effective for various medical conditions, based on available studies.

This study suggests that a novel micropatterned dermal–epidermal matrix (μDERM) enhances keratinocyte function and epidermal morphology, offering potential improvements in skin substitute design for wound healing applications.

This study found that applying both dehydrothermal treatment and carbodiimide crosslinking improved the mechanical properties of porcine acellular dermal matrix scaffolds without added cytotoxicity, suggesting potential applications in tissue engineering.

This study observed that CIP/KIP proteins play a significant role in regulating cell cycle arrest and differentiation in human hair follicles, supporting hair growth and formation in the anagen phase.

This study found that in a rat skin model, fat cells inhibited the proliferation of organoid hair follicle cells and fibroblasts but may have accelerated hair follicle cell differentiation.

In this study, intradermal injections of autologous platelet-rich fibrin matrix significantly increased hair density in patients with androgenetic alopecia at 2 and 3 months after initial treatment.

This study found that using PRP injections in skin flap reconstructions and combining acellular dermal matrix with split-thickness skin grafts improved healing and reduced complications in the surgical treatment of hidradenitis suppurativa.

This review discusses the development and application of cell-derived matrices in regenerative medicine and disease modeling, presenting various fabrication techniques and future perspectives, but reports no new results.