research Human αβ and γδ T Cells in Skin Immunity and Disease
Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.
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research Exosomal MicroRNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation
Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.
research The Senescence–Stemness Alliance: A Cancer-Hijacked Regeneration Principle
Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.
research The Silver Locus Product (Silv/gp100/Pmel17) as a New Tool for the Analysis of Melanosome Transfer in Human Melanocyte–Keratinocyte Co-Culture
The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.
research Inductive Properties of Hair Follicle Cells
Hair growth can be induced by certain cells found at the base of hair follicles, and these cells may also influence hair development and regeneration.
research Emerging Nonmetabolic Functions of Skin Fat
Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.
research Methods for the Isolation and 3D Culture of Dermal Papilla Cells from Human Hair Follicles
The document describes a way to isolate and grow human hair follicle cells in 3D to help study hair growth.
research Exploring the Thyroid-Skin Connection: Concepts, Questions, and Clinical Relevance
Thyroid function affects skin health, with a complex interaction between the two.
research Keratin Network Modifications Lead to the Mechanical Stiffening of the Hair Follicle Fiber
Changes in keratin make hair follicles stiffer.
research Tight Junction Barriers in Human Hair Follicles – Role of Claudin-1
Claudin-1 is important for the barrier function and growth of hair.
research Ephrins Negatively Regulate Cell Proliferation in the Epidermis and Hair Follicle
Ephrins slow down skin and hair follicle cell growth.
research A Primer for Studying Cell Cycle Dynamics of the Human Hair Follicle
The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.
research Recent Advances on Skin-Resident Stem/Progenitor Cell Functions in Skin Regeneration, Aging, and Cancers and Novel Anti-Aging and Cancer Therapies
New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.
research Stem Cells and Alopecia: A Review of Pathogenesis
Damaged hair follicle stem cells can cause permanent hair loss, but understanding their role could lead to new treatments.
research Hair Biology
The document explains hair biology, the causes of hair loss, and reviews various hair loss treatments.
research Transepidermal UV Radiation of Scalp Skin Ex Vivo Induces Hair Follicle Damage That Is Alleviated by Topical Treatment with Caffeine
Caffeine applied to the scalp can protect hair follicles from UV damage.
research Immune Modulation of Hair Follicle Regeneration
Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.
research Advanced Inhibition of Undesired Human Hair Growth by PPARγ Modulation
GMG-43AC may help reduce unwanted hair growth and treat certain hair loss conditions.
research Contribution of Androgens to Chronic Allograft Nephropathy Is Mediated by Dihydrotestosterone
Male hormones worsen kidney transplant damage, but blocking them helps.
research Friends Turned Foes: Angiogenic Growth Factors Beyond Angiogenesis
Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
research Divergent Proliferation Patterns of Distinct Human Hair Follicle Epithelial Progenitor Niches In Situ and Their Differential Responsiveness to Prostaglandin D2
Different human hair follicle stem cells grow at different rates and respond differently to a baldness-related compound.
research Peripheral Blood Gene Expression in Alopecia Areata Reveals Molecular Pathways Distinguishing Heritability, Disease, and Severity
Blood tests can help understand the genetic differences in people with alopecia areata, including how severe it is and if it's inherited.
research Morphology and Ultrastructure of Antler Velvet Hair and Body Hair from Red Deer (Cervus elaphus)
Antler velvet hair and body hair of red deer have different structures that help with protection and insulation.
research Engineering Cell-Derived Matrices: From 3D Models to Advanced Personalized Therapies
3D cell-derived matrices improve tissue regeneration and disease modeling.
research Pigmented Casts in Alopecia: A 2014 Study
Pigmented casts are common in several hair loss conditions and can help diagnose specific types of alopecia.
research Immunopathology of the Human Hair Follicle
The document concludes that immune system abnormalities cause alopecia areata, but the exact process is still not completely understood.
research Heat-Damaged Evaluation of Virgin Hair
Heat damages hair, with Asian hair losing more protein than Caucasian hair.
research Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development
The PP2A-B55α protein is essential for brain and skin development in embryos.
research Keratin 71 Mutations: From Water Dogs to Woolly Hair
A mutation in the KRT71 gene causes a hair disorder by disrupting hair follicle structure and texture.
research Ultrastructural Immunolocalization of Involucrin in the Medulla and Inner Root Sheath of Human Hair
Involucrin helps strengthen the inner parts of human hair.