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Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

Sulforaphane from broccoli can help protect skin from sun damage.

Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Male pattern baldness involves genetics, hormones, and needs better treatments.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

KGF and activin are crucial for skin healing and repair.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Researchers found a new gene area linked to male-pattern baldness, which, along with another gene, significantly increases the risk of hair loss in men.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Lichen planus pigmentosus causes dark skin patches and is treated by avoiding triggers and using anti-inflammatory medications.

Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.

Blocking β-catenin in skin cells improves hair growth during wound healing.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.